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Brain Sharp

product on market Capsule The Vitamin Shoppe Safety: 92/100
92/100

This product looks safe

  • Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
  • 80% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula combines B vitamins and Acetyl-L-Carnitine, which are linked to metabolic support and cognitive function. Research on Phosphatidylserine suggests moderate evidence for supporting memory and focus. Overall, the ingredient profile is supported by limited to moderate clinical evidence for cognitive enhancement.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Brain Sharp
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
80%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

25 mg (1470% DV)
19.2× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
667 mcg DFE (170% DV)
Exceeds UL by 667.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
100 mcg (4170% DV)
41.7× RDA — above typical dose 139 studies (A:1, B:44)
Market median: 500.0mg (861 products) 61 studies (A:4, B:13)
Market median: 100.0mg (108 products)

Other Ingredients

Gelatin Bamboo extract organic Carnauba Wax organic Acacia Gum Microcrystalline Cellulose
Claims

Label Claims — Verification

Unverified All Other
Unverified Qualified Health
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take three (3) capsules daily, preferable with meals.

Warnings & Precautions

Contains: Soy.

Keep out of reach of children.

Tamper evident Do not use if outer seal is broken or missing.

Warning: Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical condition.

Formulation Notes

Gluten free Dairy free Nut free

Contains: Soy.

Does not contain: Gluten, Sugar, Salt, Preservatives, Artificial Colors or Flavors.

Additional Information

Specialty

Brain Memory Energy production Focus

Store in a cool, dry place.

Consumption of phosphatidylserine may reduce the risk of cognitive dysfunction in the elderly. Very limited and preliminary scientific research suggests that phosphatidylserine may reduce the risk of cognitive dysfunction in the elderly. FDA concludes that there is little scientific evidence supporting this claim.

Visit www.vitaminshoppe.com or call 1-800-223-1216 for more information and to reorder.

Item No. VS-3451 2022754 FS 37

Metadata

Product Details

UPC / SKU7 66536 03451 2
DSLD Entry Date2018-11-21
Product TypeOther Combinations
FormCapsule
BrandThe Vitamin Shoppe
DSLD ID183950
Data Updated2026-04-11
Research

Research Evidence

153
Research Sources
55
Avg Quality
71
Systematic Review
51
Meta Analysis
19
Rct
6
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016 PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020 PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006 PubMed
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 PubMed DOI
View all evidence for Vitamin B6 →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.