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Alpha-GPC

product on market Capsule Pure Encapsulations Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Alpha-GPC serves as a precursor to acetylcholine, a neurotransmitter involved in cognitive function and memory. There is moderate evidence suggesting it may support focus and mental clarity. Current research indicates a high safety profile for most users.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Alpha-GPC
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

400 mg
Within RDA (0.7× RDA) 38 studies (A:1, B:7)

Other Ingredients

Dicalcium Phosphate hypoallergenic Plant Fiber Vegetarian Capsule Ascorbyl Palmitate Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendations: As a dietary supplement, take 2 capsules, 3 times daily, with or between meals.

Warnings & Precautions

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Keep out of the reach of children.

Use only if safety seal is intact.

Contains soy

Formulation Notes

Certified Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org

Gluten-free & Non-GMO

Contains soy

Additional Information

Store in a cool, dry place.

Scan to learn about our hypoallergenic supplements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

Neurotransmitter and phospholipid precursor: Supports cognitive health

GF

v4 code: AG6

Metadata

Product Details

UPC / SKU7 66298 00534 8
DSLD Entry Date2018-11-21
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
DSLD ID183566
Data Updated2026-04-11
Research

Research Evidence

28
Research Sources
47
Avg Quality
11
Clinical Trial
8
Rct
2
Guideline
2
Meta Analysis
2
Regulatory Source
1
Systematic Review
1
Openfda Safety
B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024 PubMed DOI
B Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.
Guideline Briefings in bioinformatics 2026 PubMed DOI
B Evidence-based clinical practice guidelines for functional dyspepsia 2021.
Guideline Journal of gastroenterology 2022 PubMed DOI
B Scientific Opinion on health claims related to choline
Regulatory Source EFSA Journal 2011 DOI
C Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials
Meta Analysis Nutrition reviews 2022 PubMed DOI
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition PubMed DOI
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition PubMed DOI
C Nutrient-based therapies for bipolar disorder: a systematic review
Systematic Review Psychotherapy and psychosomatics 2013 PubMed DOI
C The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people
Rct The British journal of nutrition 2007 PubMed
C Differential metabolism of choline supplements in adult volunteers.
Rct European journal of nutrition PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.