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TMG Trimethylglycine 1,000 mg

product on market Capsule Swanson Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade
Label

Product Label

Label for TMG Trimethylglycine 1,000 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
45
Servings
Non-Nutrient/Non-Botanical
Product Type
0%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

TMG
1 Gram(s)
Market median: 496.0mg (192 products) 20 studies — no high-quality reviews

Other Ingredients

Gelatin May contain one or more of the following
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: As a dietary supplement, take two capsules per day with water. Take with first meal of the day, preferably breakfast.

Warnings & Precautions

Warning: For adults only.

Consult your physician before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.

Keep out of reach of children.

Do not use if seal is broken.

Additional Information

Supports healthy liver function Supports detoxification Supports normal homocysteine levels Science-backed quality since 1969

Store in a cool, dry place.

Liver Health

SWU466 Rev 0 02 02 18

Metadata

Product Details

UPC / SKU0 87614 02466 0
DSLD Entry Date2018-09-21
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
BrandSwanson
DSLD ID181395
Data Updated2026-04-11
Research

Research Evidence

23
Research Sources
47
Avg Quality
18
Rct
3
Systematic Review
1
Meta Analysis
1
Clinical Trial
B Effect of Folic Acid, Betaine, Vitamin B₆, and Vitamin B12 on Homocysteine and Dimethylglycine Levels in Middle-Aged Men Drinking White Wine
Rct Nutrients 2016 PubMed DOI
C Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial
Rct Hepatology (Baltimore, Md.) 2009 PubMed DOI
C Guidelines for the diagnosis and management of cystathionine beta-synthase deficiency
Systematic Review Journal of inherited metabolic disease 2017 PubMed DOI
C Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines
Systematic Review Journal of inherited metabolic disease 2015 PubMed DOI
C Effects of low-dose B vitamins plus betaine supplementation on lowering homocysteine concentrations among Chinese adults with hyperhomocysteinemia: a randomized, double-blind, controlled preliminary clinical trial
Rct European journal of nutrition 2023 PubMed DOI
C Association of Betaine-Homocysteine S-Methyl Transferase (rs3797546 and rs3733890) polymorphisms with non-syndromic cleft lip/palate: A meta-analysis
Meta Analysis International orthodontics 2019 PubMed DOI
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition PubMed DOI
C Effect of inulin supplementation on fecal and blood metabolome in alcohol use disorder patients: A randomised, controlled dietary intervention.
Rct Clinical nutrition ESPEN PubMed DOI
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition PubMed DOI
C Fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine
Rct Cardiovascular drugs and therapy 2009 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.