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Bone Collagenizer Ultra

product on market Capsule BioSil Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

This profile includes silicon, vitamin K2, and B12, which are associated with bone mineral density and metabolic function. While some ingredients have moderate research support for skeletal health, the overall evidence coverage for this specific combination is limited. The formulation maintains a high safety profile.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Bone Collagenizer Ultra
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
20
Servings
Other Combinations
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

25 mcg (21% DV)
Within RDA (0.2× RDA) 275 studies (A:9, B:175)
50 mcg (2083% DV)
20.8× RDA — above typical dose 139 studies (A:1, B:44)
120 mg (22% DV)
Within RDA (0.2× RDA) 38 studies (A:1, B:7)
6 mg
Market median: 108.0mg (8 products) 9 studies (A:0, B:4)
300 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)

Other Ingredients

Microcrystalline Cellulose purified Water Capsule Shell
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take 2 capsules, once daily with or without food. For optimum results, take with your daily calcium supplement or a calcium rich food source.

Clinical Facts Choline-Stabilized Orthosilicic Acid (ch-OSA) Clinically Proven Dosage ch-OSA Clinically Proven for Bone 2 capsules 1 x daily Increases bone collagen formation Increases BMD (at the hip) above calcium and vitamin D alone Use in conjunction with 1000 mg of calcium and 20 mcg (900 IU) of vitamin D ch-OSA has been tested in rigorous double-blind placebo controlled clinical trials for both efficacy and safety. The results are published in peer reviewed medical journals (see insert for details).

Warnings & Precautions

Sealed for your protection. Do not use if seal is broken.

Cautions: Consult your health professional before use if you are pregnant, breastfeeding or trying to conceive, or if you are taking medication (especially anticoagulant drugs such as Warfarin/Coumadin), have a medical condition or anticipate a surgery.

Formulation Notes

The ch-OSA in Collagenizer Ultra increases bone collagen formation and increases BMD. The choline and inositol help maintain "osteo-balance," ensuring proper renewal of bone. The MK7 makes sure calcium gets delivered to the bone site. Vitamin B12 together with choline protects against collagen breakdown.

Clinically Proven ch-OSA + Inositol + MK7 + B12

Does Not Contain: Gluten, wheat, soy, yeast, dairy, sugar, starch, egg, fish, shellfish, peanuts or tree nuts, animal products, GMOs or artificial colors, preservatives or sweeteners.

Suitable for vegetarians/vegans.

Additional Information

Collagen's Crucial Role In Your Total Bone Health The National Institutes of Health reports that it takes both calcium and collagen to build strong healthy bones. Collagen makes up to 30% of your bone. Collagen serves as the "binding sites" for calcium and gives bone the pliability it needs to withstand physical stress. Age-related diminution of collagen leads to brittle bones and low BMD.

Insufficient Bone Collagen Insufficient calcium "binding sites," low BMD brittle bone and "holes" in bone (osteoporosis) Optimal Bone Collagen Optimal calcium "binding sites," optimum BMD, strong, pliable with the ability to bend-not-break Measured at the hip

Vegan Vegetarian

isura Non-GMO - Mass Spec Documentation Lab tested

Increases bone collagen formation Increases calcium binding sites Promotes bone pliability Increases bone mineral density (BMD) Boosts the effectiveness of dietary and supplemental calcium Helps maintain positive osteoblast balance Advanced calcium delivery system

U.S. Patents: #5922360, #7968528 and #8771757

Product Facts

Made in Belgium

Clinical Trial Results Results of double-blind, randomized, placebo-controlled clinical trials, with momen who added Bone Collagenizer to their daily supplements of 1000 mg of calcium and 800 IU of Vitamin D. Increase in Bone Collagen Formulation % Change in Serum P1NP Level (ug/L) 36.49 Calcium & Vitamin D 42.04 ch-OSA Calcium & Vitamin D 15.0% Increase in P1NP First 12 Months Increase in BMD at Hip Change in Bone Mineral Density -1.22 Calcium & Vitamin D +.78 ch-OSA Calcium & Vitamin D 2.0% Improvement in BMD at hip First 12 Months

R4

Metadata

Product Details

UPC / SKU5 425010 39151 4
DSLD Entry Date2018-09-21
Product TypeOther Combinations
FormCapsule
BrandBioSil
DSLD ID179798
Data Updated2026-04-11
Research

Research Evidence

281
Research Sources
54
Avg Quality
141
Meta Analysis
72
Systematic Review
45
Rct
18
Clinical Trial
2
Narrative Review
1
Other
1
Guideline
1
Openfda Safety
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Meta Analysis The Cochrane database of systematic reviews 2016 PubMed DOI
B Effects of Oral Collagen for Skin Anti-Aging: A Systematic Review and Meta-Analysis
Meta Analysis Nutrients 2023 PubMed DOI
B Transepithelial versus epithelium-off corneal crosslinking for progressive keratoconus
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Bisphosphonate therapy for osteogenesis imperfecta
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
B Punctal occlusion for dry eye syndrome
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
B Dressings and topical agents containing hyaluronic acid for chronic wound healing
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
B Efficacy of statins for osteoporosis: a systematic review and meta-analysis
Meta Analysis Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2017 PubMed DOI
B Drugs to reduce bleeding and transfusion in major open vascular or endovascular surgery: a systematic review and network meta-analysis
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
B Bisphosphonate therapy for osteogenesis imperfecta
Meta Analysis The Cochrane database of systematic reviews 2008 PubMed DOI
B Bisphosphonates for osteoporosis in primary biliary cirrhosis
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.