🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
30 Servings
Non-Nutrient/Non-Botanical Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

400 mg
📊 Market median: 200.0mg (52 products) 📚 10 studies (Tier A: 0, B: 6)
This product: 400mg

Other Ingredients

Cellulose Mannitol Hydroxypropylmethylcellulose-Phthalate Citric Acid Sodium Starch Glycolate Triacetin Croscarmellose Sodium Stearic Acid Silica yellow Ochre

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (83% of products) Nutrient (6% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) No Allergies Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested Use: As a dietary supplement, take one (1) or two (2) tablets daily, or as directed by a health care professional.

⚠️ Warnings & Precautions

Warning: Individuals using standard antidepressants, such as MAO inhibitors, SSRI's and tricyclics should consult a physician before using this dietary supplement.

Individuals with Parkinson's Disease or Bipolar Disorder should not use SAMe.

Pregnant or nursing women should consult with their physician before using this product. Caution: If you are pregnant or nursing, have a medical condition, consult your healthcare professional before using this or any other nutritional supplement.

Discontinue use if allergic reaction occurs.

Keep out of reach of children.

🧪 Formulation Notes

No: Milk, eggs, fish, crustaceans shellfish, tree nuts, peanuts, wheat, or soybeans.

Vegan

Allergen free Gluten free Non-GMO

SAMe Gold 400 mg per serving

Additional Information

SAMe Gold may be beneficial for sufferers of depression, arthritis, fibromyalgia, migraines and may aid in liver function. SAMe is essential for the production of glutathione, a powerful antioxidant that protects the body from the damaging effects of free radicals. SAMe improves the binding of neurotransmitters to their receptor sites in the brain. SAMe has been used in Europe for the treatment of cirrhosis and for the damage caused by alcohol consumption. SAMe Gold may also be useful for depression.

General Information: SAMe (S-Adenosyl-L-Methionine), is formed by an enzymatic reaction of methionine, a sulfur-containing amino acid, and adenosine triphosphate (ATP), the body's main energy molecule. SAMe occurs naturally in the human body and is involved in over forty biochemical reactions in the body. Unfortunately, SAMe levels decline with age. Supplementing with additional SAMe may protect the body from immune deficiencies.

We do not use ingredients that were produced using modern biotechnology.

Pharmaceutical grade

Promotes healthy joint function Elevates mood and emotional well-being May help detoxify the liver

REV 01-20-16

Olympian Labs, Inc. products are made with the highest quality ingredients and manufactured according to current Good Manufacturing Practices (cGMP).

Made in USA

Store in a cool, dry place.

Product Details

UPC / SKU 7 10013 03265 2
DSLD Entry Date 2018-05-24
Product Type Non-Nutrient/Non-Botanical
Form Tablet or Pill
DSLD ID 175996
Data Updated 2026-04-11

Research Evidence

12 Research Sources
58 Avg Quality Score
8 Meta Analysis
3 Systematic Review
1 Rct
B S-adenosyl-L-methionine for alcoholic liver diseases
Meta Analysis The Cochrane database of systematic reviews 2006
B S-adenosyl methionine (SAMe) for depression in adults
Meta Analysis The Cochrane database of systematic reviews 2016
B Systemic juvenile idiopathic arthritis and adult-onset Still's disease are the same disease: evidence from systematic reviews and meta-analyses informing the 2023 EULAR/PReS recommendations for the diagnosis and management of Still's disease
Meta Analysis Annals of the rheumatic diseases 2024
B SAMe-TT2R2 Score to Predict Time in Therapeutic Range of Vitamin K Antagonists in Asian and Non-Asian patients: A Systematic Review and Meta-analysis
Meta Analysis American journal of cardiovascular drugs : drugs, devices, and other interventions 2024
B S-Adenosylmethionine (SAMe) as an adjuvant therapy for patients with depression: An updated systematic review and meta-analysis
Meta Analysis General hospital psychiatry 2024
B S-adenosyl-L-methionine for alcoholic liver diseases
Systematic Review The Cochrane database of systematic reviews 2001
B WITHDRAWN: S-adenosyl-L-methionine for alcoholic liver diseases
Meta Analysis The Cochrane database of systematic reviews 2015
C S-adenosyl-L-methionine for the treatment of chronic liver disease: a systematic review and meta-analysis
Meta Analysis PloS one 2015
C S-Adenosylmethionine (SAMe) for Liver Health: A Systematic Review
Systematic Review Nutrients 2024
C SAMe-TT2R2 to Predict Clinical Outcomes and Time in Therapeutic Range in Patients on Vitamin K Antagonists: A Systematic Review and Meta-Analysis
Meta Analysis The Annals of pharmacotherapy 2024
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