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Dr. Cutler's Ultimate Age Defense

product on market Capsule True Health Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains B vitamins and an anti-glycation blend intended to support metabolic function and cellular health. Research on B vitamins is strong, though evidence for the specific anti-glycation blend is limited. The product maintains a high safety profile.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Dr. Cutler's Ultimate Age Defense
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

34 mg (2020% DV)
28.3× RDA — above typical dose 76 studies (A:0, B:33)
15 mg (750% DV)
11.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
1 mg (250% DV)
2.5× RDA — within safe limits 226 studies (A:10, B:105)
1 mg (16667% DV)
416.7× RDA — above typical dose 139 studies (A:1, B:44)
AGE Defense Anti-Glycation Blend
1000 mg
Guava (Psidium guajava) leaf extract
125 mg
Yerba Maté (Ilex paraguariensis) leaf extract
125 mg
Market median: 200.0mg (198 products) 6 studies — no high-quality reviews

Other Ingredients

Hydroxypropylmethylcellulose Silicon Dioxide Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: Take 2 capsules daily between meals or as directed by your healthcare professional.

Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN.

Formulation Notes

Contains no artificial colors, flavors or preservatives.

Additional Information

MADE IN U.S.A.

300-TUABC-A

For Support of Healthy Aging*

SCIENTIFICALLY FORMULATED DOCTOR APPROVED

STORE IN A COOL, DRY PLACE.

This product is manufactured in a NSF GMP registered facility.

Metadata

Product Details

DSLD Entry Date2012-12-21
Product TypeOther Combinations
FormCapsule
BrandTrue Health
DSLD ID16723
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.