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Circulation Factors

product on market Tablet or Pill Country Life Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 46% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Horse chestnut and butcher's broom are supported by moderate evidence for managing venous insufficiency and improving circulation. Niacin, magnesium, and calcium provide general metabolic and vascular support, though evidence for their specific role in circulation is more limited. The ingredient profile maintains a high safety rating.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Circulation Factors
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
Botanical with Nutrients
Product Type
46%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

10 mg (50% DV)
Within RDA (0.7× RDA) 196 studies (A:5, B:63)
Calcium
193 mg (19% DV)
25 mg (6% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
Market median: 285.0mg (90 products) 1 studies — no high-quality reviews
Butcher's Broom
100 mg
Grape skin extract
100 mg
Prickly Ash
100 mg
Market median: 333.0mg (166 products) 9 studies (A:0, B:2)
Market median: 120.0mg (440 products) 191 studies (A:1, B:71)
Cayenne
303 mg
Market median: 250.0mg (337 products) 127 studies (A:1, B:41)

Other Ingredients

Cellulose Stearic Acid Cellulose & Glycerin Coating Magnesium Stearate Silica Vegetable Glaze
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Directions: Adults take one (1) tablet twice daily with food or as directed by a health care professional. As a reminder, discuss the supplements and medications that you take with your health care providers.

Warnings & Precautions

Do not accept if seal is broken.

Keep out of the reach of children.

WARNING: Not to be used during pregnancy. If you are nursing, taking medication or planning a surgery, consult your doctor before using this product.

If any adverse reactions occur, stop taking the product and consult your doctor.

Formulation Notes

NO: Yeast, wheat, soy, gluten, milk, salt, sugar, preservatives or artificial color.

Gluten-Free

Additional Information

Product No. 1619 10H10L

Store between 59(0)-86(0) F.

Certified Vegan AVA(TM) American Vegetarian Association Certified GF(R) Gluten-Free Good Manufacturing Practices GMP CERTIFIED Our manufacturing supports wind power renewablechoice.com PLEASE RECYCLE

SPECIALTY SUPPLEMENTS

Tablets

Metadata

Product Details

UPC / SKU0 15794 01619 9
DSLD Entry Date2012-10-25
Product TypeBotanical with Nutrients
FormTablet or Pill
DSLD ID14042
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.