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CalDenex

product on market Tablet or Pill Nikken Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 62% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Calcium, magnesium, and vitamin D3 have strong evidence for supporting bone density and mineral absorption. Vitamin K and folate contribute to bone health and cellular function. Overall, these ingredients are well-researched, though the specific product formulation has limited clinical evidence coverage.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for CalDenex
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Tablet(s)
Serving Size
30
Servings
Multi-Vitamin and Mineral (MVM)
Product Type
62%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

900 IU (225% DV)
1.5× RDA — within safe limits 608 studies (A:16, B:251)
120 mcg (150% DV)
Within RDA (1.0× RDA) 275 studies (A:9, B:175)
120 mcg (30% DV)
Within RDA (0.3× RDA) 226 studies (A:10, B:105)
Calcium
900 mg (90% DV)
225 mg (56% DV)
Within RDA (0.5× RDA) 316 studies (A:8, B:159)
45 mcg (38% DV)
1.3× RDA — within safe limits 199 studies (A:1, B:55)
Sodium
5 mg (1% DV)
600 mcg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews

Other Ingredients

Microcrystalline Cellulose Croscarmellose Sodium Hydroxypropyl Cellulose Oleic Acid Silicon Dioxide Sodium Carboxymethylcellulose Stearic Acid Calcium Stearate DL-Alpha-Tocopherol
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommended Use: Three [3] tablets at mealtime or one [1] tablet three times a day with food.

Warnings & Precautions

If you are allergic to any of these ingredients, or are pregnant or nursing, consult a doctor before taking dietary supplements.

Keep out of reach of children.

DO NOT USE IF SEAL IS MISSING OR BROKEN.

Additional Information

NIKKEN

Made in USA

#15584 9/10

Supports healthy bones

Store in a dry place at room temperature.

Metadata

Product Details

UPC / SKU#15584
DSLD Entry Date2012-07-25
Product TypeMulti-Vitamin and Mineral (MVM)
FormTablet or Pill
BrandNikken
DSLD ID11249
Data Updated2026-04-11
Research

Research Evidence

872
Research Sources
53
Avg Quality
309
Meta Analysis
309
Clinical Trial
111
Rct
71
Systematic Review
55
Guideline
4
Cochrane Review
4
Regulatory Source
2
Other
2
Narrative Review
2
Observational
1
Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
View all evidence for Vitamin D →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.