🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 80% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
60 Servings
Other Combinations Product Type
80% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin C
200 mg (333% DV)
50 IU (167% DV)
✅ 2.2× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 33.5mg UL 1000mg
379 mg
📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)
This product: 379mg
100 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 100mg
83 mg
✅ Within RDA (0.2× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 83mg UL 3500mg

Other Ingredients

Sorbitol Stearic Acid modified Cellulose Gum Silicon Dioxide, Colloidal Magnesium Stearate

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested Use: 1 to 2 tablets twice daily with a meal.

⚠️ Warnings & Precautions

Contains soy.

Note: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.

Do not use if either tamper-evident seal is broken or missing.

Keep out of the reach of children.

🧪 Formulation Notes

Contains soy.

Additional Information

Supports liver health

Silymarin, a flavonoid complex extracted from milk thistle seeds, is an important contributor to the support of healthy liver function. The liver plays an important role in digestion, detoxification, blood sugar regulation and fat metabolism. In in vitro studies, silymarin demonstrated antioxidant activity and the ability to inhibit lipid peroxidation of cellular membranes. Silymarin also helps regulate the balance of prostaglandins in the liver. Prostaglandins are hormone-like molecules that regulate a variety of bodily functions.

SN0461 REV K101-A

Product Details

UPC / SKU 0 21078 00461 5
DSLD Entry Date 2017-12-22
Product Type Other Combinations
Form Tablet or Pill
DSLD ID 82189
Data Updated 2026-04-11

Research Evidence

69 Research Sources
55 Avg Quality Score
34 Meta Analysis
26 Systematic Review
5 Rct
3 Clinical Trial
1 Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024
View all evidence for Milk Thistle →

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