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Silymarin Plus

product on market Tablet or Pill Source Naturals Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 80% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Silymarin is supported by moderate evidence for liver health, while vitamins C and E act as antioxidants to reduce oxidative stress. Inositol and choline contribute to lipid metabolism and cellular signaling. Overall, the evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Silymarin Plus
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
60
Servings
Other Combinations
Product Type
80%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
200 mg (333% DV)
50 IU (167% DV)
2.2× RDA — within safe limits 179 studies (A:3, B:90)
379 mg
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)
100 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
83 mg
Within RDA (0.2× RDA) 38 studies (A:1, B:7)

Other Ingredients

Sorbitol Stearic Acid modified Cellulose Gum Silicon Dioxide, Colloidal Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: 1 to 2 tablets twice daily with a meal.

Warnings & Precautions

Contains soy.

Note: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.

Do not use if either tamper-evident seal is broken or missing.

Keep out of the reach of children.

Formulation Notes

Contains soy.

Additional Information

Supports liver health

Silymarin, a flavonoid complex extracted from milk thistle seeds, is an important contributor to the support of healthy liver function. The liver plays an important role in digestion, detoxification, blood sugar regulation and fat metabolism. In in vitro studies, silymarin demonstrated antioxidant activity and the ability to inhibit lipid peroxidation of cellular membranes. Silymarin also helps regulate the balance of prostaglandins in the liver. Prostaglandins are hormone-like molecules that regulate a variety of bodily functions.

SN0461 REV K101-A

Metadata

Product Details

UPC / SKU0 21078 00461 5
DSLD Entry Date2017-12-22
Product TypeOther Combinations
FormTablet or Pill
DSLD ID82189
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.