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St. John's Wort 300 mg

product on market Capsule Natural Factors HerbalFactors Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade
Label

Product Label

Label for St. John's Wort 300 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Other Combinations
Product Type
0%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 300.0mg (240 products) 20 studies — no high-quality reviews

Other Ingredients

Rice powder Gelatin capsule Magnesium Stearate Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Usage: 1 capsule 2-3 times per day with meals or as directed by a health professional.

Warnings & Precautions

Warning: For occasional use only. May cause drowsiness. Do not drive or engage in activities requiring alertness.

Do not take with other sedative medication or alcohol.

Do not exceed recommended dose except on the advice of a health professional.

Do not take if you are pregnant or breastfeeding except on the advice of a health professional. Medication may cause increased photosensitivity; avoid prolonged exposure to sunlight.

Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding, or trying to conceive, or if you are taking medication, have a medical condition, or anticipate a surgery.

Keep out of the reach of children.

Sealed for your protection. Do not use if seal is broken.

Formulation Notes

St. John's Wort extract (hypericum perforatum) is standardized to contain 0.3% hypericin.

Contains no artificial colors, preservatives, or sweeteners; no dairy, sugar, wheat, gluten, yeast, soy, egg, fish, shellfish, salt, tree nuts, or GMOs.

0.3% hypericin

Additional Information

isura Non-GMO - Mass spec Documentation - Lab tested

Scientific research shows that St. John's Wort may support mood and emotional well-being. Manufactured by Natural Factors to ensure safety and potency in accordance with Good Manufacturing Practices (GMP) of the FDA and Health Canada.

For freshness, store in a cool, dry place.

Product of Canada

Recyclable container and label.

Purity & potency guaranteed

Mood support

R5

Metadata

Product Details

UPC / SKU0 68958 04821 5
DSLD Entry Date2017-07-25
Product TypeOther Combinations
FormCapsule
DSLD ID76444
Data Updated2026-04-11
Research

Research Evidence

43
Research Sources
48
Avg Quality
16
Meta Analysis
14
Systematic Review
7
Rct
4
Regulatory Source
1
Clinical Trial
1
Openfda Safety
B St John's wort for major depression
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
B Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis
Meta Analysis Journal of affective disorders 2017 PubMed DOI
B A systematic review of St. John's wort for major depressive disorder
Meta Analysis Systematic reviews 2016 PubMed DOI
B St John's wort for depression
Systematic Review The Cochrane database of systematic reviews 2000 PubMed
B Efficacy of Pharmacological Interventions in Milder Depression: A Systematic Review and Meta-Analysis
Meta Analysis Neuropsychopharmacology reports 2025 PubMed DOI
B St John's wort for depression
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
C St John's wort for depression: meta-analysis of randomised controlled trials
Meta Analysis The British journal of psychiatry : the journal of mental science 2005 PubMed
C The effect of Hypericum perforatum on postmenopausal symptoms and depression: A randomized controlled trial
Rct Complementary therapies in medicine 2019 PubMed DOI
C Hypericum extract versus imipramine or placebo in patients with moderate depression: randomised multicentre study of treatment for eight weeks
Rct BMJ (Clinical research ed.) 1999 PubMed
C Hypericum perforatum as a cognitive enhancer in rodents: A meta-analysis
Meta Analysis Scientific reports 2016 PubMed DOI
View all evidence for St Johns Wort →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.