🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

📸

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Label Data

1 Capsule(s) Serving Size
Other Combinations Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 300.0mg (240 products) 📚 11 studies — no high-quality reviews
This product: 300mg

Other Ingredients

Rice powder Gelatin capsule Magnesium Stearate Silica

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (2% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Suggested Usage: 1 capsule 2-3 times per day with meals or as directed by a health professional.

⚠️ Warnings & Precautions

Warning: For occasional use only. May cause drowsiness. Do not drive or engage in activities requiring alertness.

Do not take with other sedative medication or alcohol.

Do not exceed recommended dose except on the advice of a health professional.

Do not take if you are pregnant or breastfeeding except on the advice of a health professional. Medication may cause increased photosensitivity; avoid prolonged exposure to sunlight.

Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding, or trying to conceive, or if you are taking medication, have a medical condition, or anticipate a surgery.

Keep out of the reach of children.

Sealed for your protection. Do not use if seal is broken.

🧪 Formulation Notes

St. John's Wort extract (hypericum perforatum) is standardized to contain 0.3% hypericin.

Contains no artificial colors, preservatives, or sweeteners; no dairy, sugar, wheat, gluten, yeast, soy, egg, fish, shellfish, salt, tree nuts, or GMOs.

0.3% hypericin

Additional Information

isura Non-GMO - Mass spec Documentation - Lab tested

Scientific research shows that St. John's Wort may support mood and emotional well-being. Manufactured by Natural Factors to ensure safety and potency in accordance with Good Manufacturing Practices (GMP) of the FDA and Health Canada.

For freshness, store in a cool, dry place.

Product of Canada

Recyclable container and label.

Purity & potency guaranteed

Mood support

R6

Product Details

UPC / SKU 0 68958 04820 8
DSLD Entry Date 2017-07-25
Product Type Other Combinations
Form Capsule
DSLD ID 76441
Data Updated 2026-04-11

Research Evidence

43 Research Sources
48 Avg Quality Score
16 Meta Analysis
14 Systematic Review
7 Rct
4 Regulatory Source
1 Clinical Trial
1 Openfda Safety
B St John's wort for major depression
Systematic Review The Cochrane database of systematic reviews 2008
B Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis
Meta Analysis Journal of affective disorders 2017
B A systematic review of St. John's wort for major depressive disorder
Meta Analysis Systematic reviews 2016
B St John's wort for depression
Systematic Review The Cochrane database of systematic reviews 2000
B Efficacy of Pharmacological Interventions in Milder Depression: A Systematic Review and Meta-Analysis
Meta Analysis Neuropsychopharmacology reports 2025
B St John's wort for depression
Meta Analysis The Cochrane database of systematic reviews 2005
C St John's wort for depression: meta-analysis of randomised controlled trials
Meta Analysis The British journal of psychiatry : the journal of mental science 2005
C The effect of Hypericum perforatum on postmenopausal symptoms and depression: A randomized controlled trial
Rct Complementary therapies in medicine 2019
C Hypericum extract versus imipramine or placebo in patients with moderate depression: randomised multicentre study of treatment for eight weeks
Rct BMJ (Clinical research ed.) 1999
C Hypericum perforatum as a cognitive enhancer in rodents: A meta-analysis
Meta Analysis Scientific reports 2016
View all evidence for St Johns Wort →

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