🟢 90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 18% of ingredients have research evidence
B Label Compliance Grade

Product Label

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Safety Alerts

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

0.5 fl. Oz. Serving Size
34 Servings
Other Combinations Product Type
18% Evidence Coverage

Supplement Facts — Evidence Check

Calories
10 Calorie(s)
Total Carbohydrates
2 Gram(s) (1% DV)
Sugar
2 Gram(s)
0.1 mg (3% DV)
✅ Within RDA (0.1× RDA of 1.3 mg) 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 0.1mg
12 mcg (3% DV)
📊 Market median: 667.0mg (446 products) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.012mg UL 1.0mg
Sodium
25 mg (1% DV)
Proprietary Blend
13.9 Gram(s)
Water
Lemon essence
Capsicum extract

Other Ingredients

Fructose DL-Malic Acid

Label Claims — Verification

All Other
All Other (99% of products) Structure/Function (85% of products) Nutrient (48% of products) No Claim (1% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

How to use the specially sedigned cap to prevent dripping 1 Remove the twist-off cap (turning in a counter-clockwise motion) and discard. 2 Replace with enclosed flip-top cap (turning in a clockwise motion). Enjoy easy opening and closing while the flip-top cap keeps the bottle clean!

Serving Suggestions Shake well before each use. The suggested daily serving is 1/2 fl. oz., which is the middle line on the enclosed measuring cup. Store in a cool, dry place until opened. After opening, reseal with the cap and refrigerate. Use within 45 days after opening.

Additional Information

GMP

Gf Certified Gluten-free

No artificial preservatives (US patent no. 8,187,641)

Store in a cool, dry place until opened. After opening, reseal with the cap and refrigerate.

Refrigerate after opening

Product of Japan

This product was manufactured at a certified factory that meets the dietary/food supplement Good Manufacturing Practice (GMP) standards of the Japan Health Food and Nutrition Food Association.

Box contains 80% recycled paper.

SU4-2S

Product Details

UPC / SKU 0 29918 01313 1
DSLD Entry Date 2017-07-25
Product Type Other Combinations
Form Liquid
DSLD ID 75745
Data Updated 2026-04-11

Research Evidence

22 Research Sources
49 Avg Quality Score
8 Rct
4 Meta Analysis
4 Clinical Trial
3 Systematic Review
1 Cochrane Review
1 Regulatory Source
B Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
Systematic Review BMJ open 2024
B Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2022
B Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
Systematic Review The Cochrane database of systematic reviews 2010
B Riboflavin supplements for blood pressure lowering in adults.
Cochrane Review The Cochrane database of systematic reviews
B Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2022
C Prophylaxis of migraine headaches with riboflavin: A systematic review
Systematic Review Journal of clinical pharmacy and therapeutics 2017
C Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
Rct Cephalalgia : an international journal of headache 2010
C The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
Meta Analysis International ophthalmology 2023
C Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
Meta Analysis The ocular surface 2014
C Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
Rct The journal of headache and pain 2015
View all evidence for Riboflavin →

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