O.P.A.
100/100
This product looks safe
- No ingredients exceed tolerable upper intake levels
- 100% of ingredients have research evidence
A
Label Compliance Grade
Product Label
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Label Data
4 mL
Serving Size
15
Servings
Other Combinations
Product Type
100%
Evidence Coverage
Supplement Facts — Evidence Check
100 mcg
(6% DV)
✅ Within RDA (0.1× RDA of 1.3 mg)
📚 12 studies (Tier A: 0, B: 1)
125 mg
(13% DV)
✅ Within RDA (0.2× RDA of 700 mg)
📚 12 studies (Tier A: 0, B: 3)
21 mg
📊 Market median: 550.0mg (217 products)
📚 29 studies (Tier A: 0, B: 5)
Other Ingredients
Water, Purified
Label Claims — Verification
❓
All Other
All Other (99% of products)
Structure/Function (85% of products)
Nutrient (48% of products)
No Claim (1% of products)
Target Groups
Adult (18 - 50 Years)
Women (not pregnant or lactating)
Product Information
📋 Directions for Use
Directions: Four to five droppers diluted with water daily, or more, as directed by a health care professional.
⚠️ Warnings & Precautions
Sold only for dispensing by a licensed health care professional.
Not to be used by pregnant or lactating women.
Do not use if seal around cap is broken or missing.
Keep out of reach of children.
🧪 Formulation Notes
Progressive Laboratories packaged this product in its 3rd party GMP-inspected facility. (Good Manufacturing Practices)
Additional Information
Certified GMP Compliant GMP Good Manufacturing Practices 21 CFR 111
Product Details
UPC / SKU
3 51821 00414 3
DSLD Entry Date
2023-11-22
Product Type
Other Combinations
Form
Liquid
DSLD ID
299204
Data Updated
2026-04-11
Research Evidence
22
Research Sources
49
Avg Quality Score
8
Rct
4
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Cochrane Review
1
Regulatory Source
B
Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
B
Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
B
Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
B
Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
C
Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
C
The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
C
Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
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