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O.P.A.

product on market Liquid Progressive Professional from Progressive Laboratories Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Riboflavin and phosphorus are essential nutrients supporting cellular energy production and bone health, while inositol plays a role in cellular signaling. Research provides strong evidence for the fundamental physiological functions of these components. However, overall evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for O.P.A.
Open Full PDF View on NIH DSLD →
Details

Label Data

4 mL
Serving Size
15
Servings
Other Combinations
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

100 mcg (6% DV)
Within RDA (0.1× RDA) 13 studies (A:0, B:1)
125 mg (13% DV)
Within RDA (0.2× RDA) 13 studies (A:0, B:3)
21 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)

Other Ingredients

Water, Purified
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Directions: Four to five droppers diluted with water daily, or more, as directed by a health care professional.

Warnings & Precautions

Sold only for dispensing by a licensed health care professional.

Not to be used by pregnant or lactating women.

Do not use if seal around cap is broken or missing.

Keep out of reach of children.

Formulation Notes

Progressive Laboratories packaged this product in its 3rd party GMP-inspected facility. (Good Manufacturing Practices)

Additional Information

Certified GMP Compliant GMP Good Manufacturing Practices 21 CFR 111

Metadata

Product Details

UPC / SKU3 51821 00414 3
DSLD Entry Date2023-11-22
Product TypeOther Combinations
FormLiquid
BrandProgressive Professional from Progressive Laboratories
DSLD ID299204
Data Updated2026-04-11
Research

Research Evidence

22
Research Sources
49
Avg Quality
8
Rct
4
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Cochrane Review
1
Regulatory Source
B Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
Systematic Review BMJ open 2024 PubMed DOI
B Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2022 PubMed DOI
B Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
Systematic Review The Cochrane database of systematic reviews 2010 PubMed DOI
B Riboflavin supplements for blood pressure lowering in adults.
Cochrane Review The Cochrane database of systematic reviews PubMed DOI
B Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2022 PubMed DOI
C Prophylaxis of migraine headaches with riboflavin: A systematic review
Systematic Review Journal of clinical pharmacy and therapeutics 2017 PubMed DOI
C Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
Rct Cephalalgia : an international journal of headache 2010 PubMed DOI
C The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
Meta Analysis International ophthalmology 2023 PubMed DOI
C Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
Meta Analysis The ocular surface 2014 PubMed DOI
C Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
Rct The journal of headache and pain 2015 PubMed DOI
View all evidence for Riboflavin →
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Riboflavin research Best Riboflavin All Riboflavin products More from Progressive Professional from Progressive Laboratories View on NIH DSLD →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.