🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 75% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Veg Capsule(s) Serving Size
Other Combinations Product Type
75% Evidence Coverage

Supplement Facts — Evidence Check

1000 mcg (41667% DV)
📊 416.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 1.0mg
📊 Market median: 500.0mg (861 products) 📚 60 studies (Tier A: 4, B: 13)
This product: 200mg
30 mg
📊 Market median: 100.0mg (283 products) 📚 142 studies (Tier A: 1, B: 64)
This product: 30mg UL 1200mg
BioPQQ
20 mg

Other Ingredients

Cellulose Cellulose powder Stearic Acid Silica

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (89% of products) Nutrient (56% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested Usage: Take 1 capsule daily with a meal.

⚠️ Warnings & Precautions

Consult physician if pregnant/nursing, taking medication (especially warfarin or acenocoumerol), or have a medical condition.

Keep out of reach of children.

Do not eat freshness packet. Keep in bottle.

Not manufactured with wheat, gluten, soy, corn, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Caution: For adults only.

🧪 Formulation Notes

BioPQQ

Vegetarian/Vegan

Not manufactured with wheat, gluten, soy, corn, milk, egg, fish, shellfish or tree nut ingredients.

Non-GMO

CoQ10 and Acetyl-L-Carnitine have been included for their critical roles in mitochondrial function and energy production.*

Additional Information

CODE 3168 V3

Cognitive support*

~ Free radical scavenger* ~ Supports mitochondrial function*

Non-GMO

GMP QUALITY ASSURED

General Health

Family owned since 1968.

Mitochondria are the organelles that produce almost all of the cellular energy the body requires. While present in all cells, organs like the heart and brain are particularly dense with mitochondria due to their high energy demands. Pyrroloquinoline Quinone (PQQ) is a B Vitamin-like enzyme cofactor that helps to protect mitochondria from oxidative stress and promotes the generation of new mitochondria within cells.* PQQ may thus help to maintain robust cellular energy production, support heart health, and promote normal cognitive function.*

Product Details

UPC / SKU 7 33739 03168 6
DSLD Entry Date 2017-02-24
Product Type Other Combinations
Form Capsule
Brand NOW
DSLD ID 71086
Data Updated 2026-04-11

Research Evidence

237 Research Sources
53 Avg Quality Score
83 Meta Analysis
74 Systematic Review
45 Rct
29 Clinical Trial
2 Guideline
2 Regulatory Source
1 Openfda Safety
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
A Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency
Systematic Review The Cochrane database of systematic reviews 2018
A Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression
Meta Analysis Nutrients 2021
A Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta-analysis
Systematic Review Irish journal of medical science 2024
B Helicobacter pylori infection and micronutrient deficiency in pregnant women: a systematic review and meta-analysis
Meta Analysis BMJ open gastroenterology 2020
B Vitamin B12 supplementation during pregnancy for maternal and child health outcomes
Systematic Review The Cochrane database of systematic reviews 2024
B A comprehensive review and meta-regression analysis of randomized controlled trials examining the impact of vitamin B12 supplementation on homocysteine levels
Meta Analysis Nutrition reviews 2024
B Relationship between vitamin B12 levels and motor development: A systematic review
Systematic Review Clinical nutrition ESPEN 2024
B Vitamin B12, folate, and homocysteine in metabolic syndrome: a systematic review and meta-analysis
Meta Analysis Frontiers in endocrinology 2023
View all evidence for Vitamin B12 →

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