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Thermo Igniter 12x

product on market Capsule GNC Pro Performance AMP Safety: 90/100
90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Niacin supports energy metabolism, while thermogenic blends typically aim to increase caloric expenditure. However, the evidence coverage for this specific formulation is very limited. Research on these combined ingredients for weight loss generally shows moderate to low efficacy.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for Thermo Igniter 12x
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Red Capsule(s)
Serving Size
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

20 mg (100% DV)
1.4× RDA — within safe limits 196 studies (A:5, B:63)
Proprietary Thermogenic Blend
243.34 mg

Other Ingredients

Cellulose Gelatin Magnesium Stearate Silica Titanium Dioxide Artificial Colors
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, for optimal health benefits, take the contents of one packet daily with food every morning. On workout days, for individuals looking to maximize energy production, the Thermo Igniter 12x (red capsule) can be taken 30-60 minutes prior to exercise.

Warnings & Precautions

Total caffeine per capsule 200 mg.

Warning: Use only as directed. Do not exceed recommended daily intake.

Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery.

Keep out of reach of children.

Formulation Notes

Total caffeine per capsule 200 mg.

Thermo Igniter 12x This exact blend has been clinically shown to help you burn 12 times more calories and increase metabolism before, during, and after excercise.

No Artificial flavors, no wheat, gluten free, no dairy, yeast free.

Additional Information

Conforms to USP <2091> for weight. Meets USP <2040> disintegration.

Several high-quality formulas in one convenient pack for maximum training support to help support a lean, ripped physique.

Burn up to 12 times more calories! 12 Times more calories burn Difference in calories (KCAL) burned Placebo GNC Thermo Igniter 12X In a randomized, double-blind, placebo-controlled study of 112 healthy volunteers, subjects taking the GNC vitamin and mineral blends for six weeks experienced significant improvements in serum levels of certain key nutrients compared to a placebo and a basic multivitamin formula based upon multivariate statistical analyses of a group of B vitamins (thiamin, niacin, riboflavin, pantothenic acid, biotin, folic acid and vitamins B-6 and B-12) and key antioxidants and carotenoids (a group of beta-carotene, alpha-tocopherol, selenium, lutein and lycopene). Statistical improvements in SF-36 vitality and mental health scores were also observed compared to placebo. In a double-blind, randomized, placebo-controlled, cross-over study, 25 subjects exercised on a treadmill two times. On the first occasion, subjects took thermo igniter 12x 60 minutes before exercise. On the second occasion, they took a placebo. Subjects using thermo igniter 12x burned three times more calories before, 3% more calories during, and 12 times more calories for up to one hour after exercise compared to using placebo.

Clinically researched

Includes multivitamin plus lean muscle support

Burns up to 12x more calories and increases metabolism Helps regulate excess water

CODE 208912 EQG

Each pak contains: Thermo Igniter 12x

Actual Size

GF Gluten free

Store in a cool, dry place.

GNC Quality Commitment Since 1935, GNC has been the leader in the development of superior nutritional supplements. Our products are produced using only fresh, high-quality ingredients and are manufactured under the strictest quality controls.

GNC Guarnatee If you are not 100% completely satisfied, return the unused portion of the product with your receipt to a GNC store within 30 days. Our trained sales staff will either refund your purchase price or, if you prefer, assist you in finding a replacement product to help you live well.

Metadata

Product Details

DSLD Entry Date2017-02-24
Product TypeOther Combinations
FormCapsule
DSLD ID70327
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.