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Advanced Collagen

product on market Tablet or Pill Nature's Bounty Optimal Solutions Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Vitamin C and biotin are supported by moderate to strong evidence for supporting collagen synthesis and nail health. The protein content provides the necessary amino acids for structural support. Overall, the evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Advanced Collagen
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Tablet(s)
Serving Size
30
Servings
Other Combinations
Product Type
33%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
10 Calorie(s)
Total Carbohydrates
1 Gram(s) (1% DV)
Protein
1 Gram(s) (2% DV)
Vitamin C
90 mg (150% DV)
450 mcg (150% DV)
15.0× RDA — above typical dose 27 studies (A:0, B:11)
Calcium
156 mg (16% DV)
3 mg (150% DV)
3.3× RDA — above typical dose (UL: 10 mg) 37 studies (A:0, B:11)
Sodium
15 mg (1% DV)
Market median: 20.0mg (931 products) 234 studies (A:1, B:90)

Other Ingredients

Vegetable Cellulose Dicalcium Phosphate Contains <2% of:
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS: For adults, take three (3) tablets daily on an empty stomach.

Warnings & Precautions

WARNING: Not intended for use by pregnant or nursing women. If you are taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Formulation Notes

Vitamin C, Copper & Biotin

No Artificial Flavor or Sweetener, No Preservatives, No Starch, No Milk, No Lactose, No Soy, No Gluten, No Wheat, No Yeast, No Fish.

Additional Information

Vital Nutrients to Support Natural Beauty*

Vitamin C, Copper and Biotin support your natural beauty from within.* Collagen is a substance rich in amino acids, which the body needs to maintain overall health.* Copper, an essential trace mineral, plays a significant role in the synthesis of collagen.* Vitamin C helps support natural collagen production in the body for healthy skin, while biotin helps maintain healthy nails and hair.*

SA 4599 00A B52556

Prod. No. 4599 SA 4599 00A B52556 Part No. 22-04601

Store at room temperature.

Guaranteed Quality Laboratory Tested

Beauty Formula

Healthy Aging

Vital Nutrients to Support Natural Beauty*

Metadata

Product Details

UPC / SKU0 74312 04599 8
DSLD Entry Date2016-09-22
Product TypeOther Combinations
FormTablet or Pill
BrandNature's Bounty Optimal Solutions
DSLD ID65024
Data Updated2026-04-11
Research

Research Evidence

281
Research Sources
54
Avg Quality
141
Meta Analysis
72
Systematic Review
45
Rct
18
Clinical Trial
2
Narrative Review
1
Other
1
Guideline
1
Openfda Safety
A Vascular closure devices for femoral arterial puncture site haemostasis
Meta Analysis The Cochrane database of systematic reviews 2016 PubMed DOI
B Effects of Oral Collagen for Skin Anti-Aging: A Systematic Review and Meta-Analysis
Meta Analysis Nutrients 2023 PubMed DOI
B Transepithelial versus epithelium-off corneal crosslinking for progressive keratoconus
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Bisphosphonate therapy for osteogenesis imperfecta
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
B Punctal occlusion for dry eye syndrome
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
B Dressings and topical agents containing hyaluronic acid for chronic wound healing
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
B Efficacy of statins for osteoporosis: a systematic review and meta-analysis
Meta Analysis Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2017 PubMed DOI
B Drugs to reduce bleeding and transfusion in major open vascular or endovascular surgery: a systematic review and network meta-analysis
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
B Bisphosphonate therapy for osteogenesis imperfecta
Meta Analysis The Cochrane database of systematic reviews 2008 PubMed DOI
B Bisphosphonates for osteoporosis in primary biliary cirrhosis
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
View all evidence for Collagen →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.