Age (Age Defense Formula) by Prime — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
80% of ingredients have research evidence

A Label Compliance Grade

Product Label

📄 Open Full PDF View on NIH DSLD →

📸

Have a supplement label? Find it here.

Upload a photo of any supplement label to search our database of 92,312 products.

Label Data

3 Tablet(s) Serving Size

30 Servings

Other Combinations Product Type

80% Evidence Coverage

Supplement Facts — Evidence Check

Thiamine

55 mg (3667% DV)

📊 45.8× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 55mg

Taurine

1000 mg

📊 Market median: 500.0mg (180 products) 📚 5 studies (Tier A: 0, B: 1)

This product: 1000mg

American Ginseng root extract

500 mg

📊 Market median: 450.0mg (390 products) 📚 155 studies (Tier A: 0, B: 63)

This product: 500mg

Cinnamon bark extract

250 mg

N-Acetylcysteine

200 mg

📊 Market median: 600.0mg (7 products) 📚 39 studies (Tier A: 2, B: 13)

This product: 200mg

Other Ingredients

Dicalcium Phosphate Microcrystalline Cellulose copovidone Stearic Acid Croscarmellose Sodium Magnesium Stearate Silica coating

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Directions for use: Take 3 tablets with the first meal of the day.

⚠️ Warnings & Precautions

KEEP OUT OF THE REACH OF CHILDREN.

Warning: If you are currently taking warfarin (Coumadin) or other antiplatelet/anticoagulant medications, nitroglycerin (Nitrostat), or have a history of estrogen sensitive cancers, you should not take this product. If you are taking antidiabetic drugs or any other prescription drugs, have diabetes or an ongoing medical condition, you should consult your physician before using this product. Women who are pregnant or breastfeeding should not use this product.

Do not use if safety seal is broken or missing.

Additional Information

Protect from heat, light and moisture. Store at 15-30°C (59-86°F).

Code: 13113/13113NM 0809

Lot #: Best when used by:

marketamerica Built on Product. Powered by People.

Product Details

DSLD Entry Date 2012-02-23

Product Type Other Combinations

Form Tablet or Pill

Brand Prime

DSLD ID 6173

Data Updated 2026-04-11

Research Evidence

100 Research Sources

56 Avg Quality Score

48 Systematic Review

30 Meta Analysis

13 Rct

6 Clinical Trial

1 Cochrane Review

1 Regulatory Source

B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol

Systematic Review The Cochrane database of systematic reviews 2013

PubMed DOI Cochrane

B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials

Systematic Review Nutritional neuroscience 2023

PubMed DOI

B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis

Meta Analysis BMJ open 2022

PubMed DOI

B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024

PubMed DOI

B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis

Systematic Review Intensive care medicine 2022

PubMed DOI

B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis

Meta Analysis Pain medicine (Malden, Mass.) 2020

PubMed DOI

B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis

Meta Analysis Critical care medicine 2021

PubMed DOI

B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Complementary therapies in medicine 2022

PubMed DOI

B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis

Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023

PubMed DOI

B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse

Systematic Review The Cochrane database of systematic reviews 2004

PubMed Cochrane

View all evidence for Thiamine →