St. John's Wort Extract Caps 300 mg

product on market Capsule Life Extension 🟢 Safety: 100/100
Brand: Life Extension
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

Label for St. John's Wort Extract Caps 300 mg
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Label Data

1 Vegetarian Capsule(s) Serving Size
Botanical Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

300 mg
📊 Market median: 300.0mg (240 products) 📚 11 studies — no high-quality reviews
This product: 300mg

Other Ingredients

Rice Flour Vegetable Cellulose Ascorbyl Palmitate

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (2% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Read the entire label and follow directions carefully prior to use. DIRECTIONS: Take one (1) capsule one or twice daily on an empty stomach, or as recommended by a healthcare practitioner.

⚠️ Warnings & Precautions

CAUTION: Because St. John's Wort may have numerous drug interactions (most commonly, MAOIs and SSRIs) consult your healthcare provider before taking this product if you are taking prescription medications.

WARNINGS: -Keep out of reach of children.

-DO NOT EXCEED RECOMMENDED DOSE. -Do not purchase if outer seal is broken or damaged.

-When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition of if you are pregnant or lactating.

Avoid prolonged exposure to UV radiation (e.g. sunlight, tanning) when using this product.

🧪 Formulation Notes

0.3 Hypericin

Additional Information

Scan for product info

Store tightly closed in a cool, dry place.

Q01396C

Supports Mental Well-Being*

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Product Details

UPC / SKU 7 37870 13966 9
DSLD Entry Date 2016-04-22
Product Type Botanical
Form Capsule
Brand Life Extension
DSLD ID 59201
Data Updated 2026-04-11

Research Evidence

43 Research Sources
48 Avg Quality Score
16 Meta Analysis
14 Systematic Review
7 Rct
4 Regulatory Source
1 Clinical Trial
1 Openfda Safety
B St John's wort for major depression
Systematic Review The Cochrane database of systematic reviews 2008
PubMed DOI
B Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis
Meta Analysis Journal of affective disorders 2017
PubMed DOI
B A systematic review of St. John's wort for major depressive disorder
Meta Analysis Systematic reviews 2016
PubMed DOI
B St John's wort for depression
Systematic Review The Cochrane database of systematic reviews 2000
PubMed
B Efficacy of Pharmacological Interventions in Milder Depression: A Systematic Review and Meta-Analysis
Meta Analysis Neuropsychopharmacology reports 2025
PubMed DOI
B St John's wort for depression
Meta Analysis The Cochrane database of systematic reviews 2005
PubMed
C St John's wort for depression: meta-analysis of randomised controlled trials
Meta Analysis The British journal of psychiatry : the journal of mental science 2005
PubMed
C The effect of Hypericum perforatum on postmenopausal symptoms and depression: A randomized controlled trial
Rct Complementary therapies in medicine 2019
PubMed DOI
C Hypericum extract versus imipramine or placebo in patients with moderate depression: randomised multicentre study of treatment for eight weeks
Rct BMJ (Clinical research ed.) 1999
PubMed
C Hypericum perforatum as a cognitive enhancer in rodents: A meta-analysis
Meta Analysis Scientific reports 2016
PubMed DOI
View all evidence for St Johns Wort →

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