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St. John's Wort Extract Caps 300 mg

product on market Capsule Life Extension Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade
Label

Product Label

Label for St. John's Wort Extract Caps 300 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Vegetarian Capsule(s)
Serving Size
Botanical
Product Type
0%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 300.0mg (240 products) 20 studies — no high-quality reviews

Other Ingredients

Rice Flour Vegetable Cellulose Ascorbyl Palmitate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Read the entire label and follow directions carefully prior to use. DIRECTIONS: Take one (1) capsule one or twice daily on an empty stomach, or as recommended by a healthcare practitioner.

Warnings & Precautions

CAUTION: Because St. John's Wort may have numerous drug interactions (most commonly, MAOIs and SSRIs) consult your healthcare provider before taking this product if you are taking prescription medications.

WARNINGS: -Keep out of reach of children.

-DO NOT EXCEED RECOMMENDED DOSE. -Do not purchase if outer seal is broken or damaged.

-When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition of if you are pregnant or lactating.

Avoid prolonged exposure to UV radiation (e.g. sunlight, tanning) when using this product.

Formulation Notes

0.3 Hypericin

Additional Information

Scan for product info

Store tightly closed in a cool, dry place.

Q01396C

Supports Mental Well-Being*

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Metadata

Product Details

UPC / SKU7 37870 13966 9
DSLD Entry Date2016-04-22
Product TypeBotanical
FormCapsule
BrandLife Extension
DSLD ID59201
Data Updated2026-04-11
Research

Research Evidence

43
Research Sources
48
Avg Quality
16
Meta Analysis
14
Systematic Review
7
Rct
4
Regulatory Source
1
Clinical Trial
1
Openfda Safety
B St John's wort for major depression
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
B Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis
Meta Analysis Journal of affective disorders 2017 PubMed DOI
B A systematic review of St. John's wort for major depressive disorder
Meta Analysis Systematic reviews 2016 PubMed DOI
B St John's wort for depression
Systematic Review The Cochrane database of systematic reviews 2000 PubMed
B Efficacy of Pharmacological Interventions in Milder Depression: A Systematic Review and Meta-Analysis
Meta Analysis Neuropsychopharmacology reports 2025 PubMed DOI
B St John's wort for depression
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
C St John's wort for depression: meta-analysis of randomised controlled trials
Meta Analysis The British journal of psychiatry : the journal of mental science 2005 PubMed
C The effect of Hypericum perforatum on postmenopausal symptoms and depression: A randomized controlled trial
Rct Complementary therapies in medicine 2019 PubMed DOI
C Hypericum extract versus imipramine or placebo in patients with moderate depression: randomised multicentre study of treatment for eight weeks
Rct BMJ (Clinical research ed.) 1999 PubMed
C Hypericum perforatum as a cognitive enhancer in rodents: A meta-analysis
Meta Analysis Scientific reports 2016 PubMed DOI
View all evidence for St Johns Wort →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.