🟢 90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Safety Alerts

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

1 Caplet(s) Serving Size
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

20 mg (100% DV)
✅ 1.4× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 20mg UL 35mg
Proprietary Thermogeneic Blend
238.34 mg

Other Ingredients

Cellulose Gelatin Titanium Dioxide Artificial Colors

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult Male (18-50 Years) Gluten Free

Product Information

📋 Directions for Use

DIRECTIONS: As a dietary supplement, take the contents of one pak 30-60 minutes pre-workout. On non-training days, take the contents of one pak first thing in the morning with food. Do not exceed one pak daily.

⚠️ Warnings & Precautions

Consult your physician prior to using this product if you are pregnant, nursing, taking medication, allergic or contraindicated to aspirin, or have a medical condition. Discontinue use two weeks prior to surgery, or if upset stomach occurs.

Consult your physician prior to using this product if you are pregnant, nursing, taking medication, allergic or contraindicated to aspirin, or have a medical condition. Discontinue use two weeks prior to surgery, or if upset stomach occurs.

KEEP OUT OF REACH OF CHILDREN.

🧪 Formulation Notes

Total caffeine per serving is 200 mg.

No Wheat, No Gluten, No Dairy, Yeast Free.

Additional Information

?In a double blind, randomized, placebo controlled cross-over study, 25 subjects exercised on a treadmill on two occasions. On one occasion the subjects took Thermo Igniter 12x and on the second occasion, they took a placebo. When the subjects took Thermo Igniter 12x, they burned three times more calories before, 3% more calories during and 12 times more calories for up to one hour after exercise compared to when they took the placebo.

ACTUAL SIZE

Thermo Igniter 12X

Thermo Igniter 12X – Push your performance to higher levels, increase energy and speed up metabolism.* This clinically proven, proprietary thermogenic blend has been shown to help you burn 12 times more calories? and increase your metabolism before, during and after exercise. In addition, just one capsule supports improved endurance and performance to help your body work longer and harder than ever before.

Capsimax(TM)

GNC QUALITY COMMITMENT GNC, the leader in the development and manufacture of dietary supplements, is committed to producing the highest quality products available. This commitment begins with quality designed supplement formulations. Every raw material that goes into a GNC supplement is guaranteed as to quality and potency. Each product is dated and then shipped immediately to our stores, so you can be sure you are purchasing the freshest supplements available. At GNC, we extend our quality commitment to you by offering our money-back guarantee.

To maximize total endurance and energy support, use with: • Amplified Endurance Booster – loaded with electrolytes, carbohydrates and BCAA to replenish glycogen stores fast* • Amplified 100% Whey Protein – with fast-absorbing protein to fuel your training*

Clinically Researched^

Store in a cool, dry place.

ADVANCED MUSCLE PERFORMANCE

ADVANCED SPORTS VITAMIN SYSTEM TO AMPLIFY ENDURANCE WITH OVER 50 POWERFUL INGREDIENTS*

CODE 331311 CMG

Daily Endurance Energy Stamina

Each pak contains:

GNC GUARANTEE Use any GNC supplement for as little as 10 days. If you are not 100% completely satisfied, return the unused portion of the product with proof of purchase to your GNC store for a complete refund of your purchase price. No questions asked!

Product Details

DSLD Entry Date 2012-02-23
Product Type Other Combinations
Form Capsule
Bundle Mega Men Powered Endurance Vitapak Program
DSLD ID 5820
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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