🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

Have a supplement label? Find it here.

Upload a photo of any supplement label to search our database of 92,312 products.

Label Data

4 Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
33% Evidence Coverage

Supplement Facts — Evidence Check

20 mg (100% DV)
✅ 1.4× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 20mg UL 35mg
📊 Market median: 500.0mg (143 products)
This product: 3300mg
Circulatory Pump Blend
380 mg

Other Ingredients

Cellulose Enteric Coating Mica Artificial Colors Vegetable Acetoglycerides natural Mint flavor Sucralose

Label Claims — Verification

All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

DIRECTIONS: As a dietary supplement, take four tablets daily with 8 fl. oz. of water 30-60 minutes before your workout. On non-training days, take first thing in the morning with water.

⚠️ Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN.

Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition. Discontinue use two weeks prior to surgery.

WARNING: Use only as directed. Do not exceed recommended daily intake.

🧪 Formulation Notes

No Sugar, No Artificial Flavors, No Wheat, No Gluten, No Soy, No Dairy, Yeast Free.

Additional Information

Store in a cool, dry place.

• 20% More Power Output at the Fatigue Barrier During Intense Training^* • 3g Full Potency Micronized Arginine to Amplify Nitric Oxide Hemodilation Effects* • Maximizes Muscle Performance Capacity*

ADVANCED MUSCLE PERFORMANCE

Amplified Maxertion N.O.(TM) - What’s the ‘pump’ All About? We’ve taken the pump to a whole new level – new and improved Amplified Maxertion N.O.(TM), GNC’s triple action N.O. pump formula! It features a clinically researched formula proven to intensify your workouts while giving you the extra power to help you push through the wall…going above and beyond your regular workout.^* GNC’s best N.O. amplifier just got even better with an added blood vessel dilator. Amplified Maxertion N.O.(TM) Evolution It’s a fact that when Nitric Oxide is released in the body, blood vessels expand allowing more oxygen and nutrients to surge to each muscle cell. Many supplements tout that they can help you achieve better pumps to your muscles for longer, more efficient workouts. Why is Amplified Maxertion N.O.(TM) different? It all begins with innovative technology proven to AMPlify effects and three vital N.O. potentiating ingredients. New and Improved Circulatory Pump Blend – Featuring clinically studied ResVida(R) resveratrol, shown to significantly enhance blood vessel dilation to help facilitate blood flow.~ This is important to help drive more oxygen and nutrient-rich blood through the body for more efficient muscle pumps!* This blend also features MegaNatural(R)-BP(TM), a clinically studied grape seed extract, that acts as an endothelial modulator to support circulation.* Micronized Arginine – This superior formula uses MicroSorb(TM) Amino Technology for enhanced absorption of arginine – a key precursor to Nitric Oxide. MicroSorb(TM) Amino Technology takes large arginine molecules and pulverizes them into smaller micronized particles. As a result, this potent N.O. activator is easier to absorb and more effective at enhancing you workout.* PEG-Arginine System – To raise the bar even higher, this formula also boasts a patent-pending PEG-Arginine system designed to further enhance the absorption of N.O. stimulating ingredients and contribute to the clinically proven effects. It also activates Nitric Oxide synthase, which is the enzyme in the body that dilates blood vessels and ignites N.O. synthesis in the muscles.*

CODE 830011 LLG

Conforms to USP <2091> for weight.

Daily Pre-Workout Power Stamina

GNC GUARANTEE Use any GNC supplement for as little as 10 days. If you are not 100% completely satisfied, return the unused portion of the product with proof of purchase to your GNC store for a complete refund of your purchase price. No questions asked!

NEW

Nitric oxide enhancer

NOW WITH A PUMP ENHANCING BLOOD VESSEL DILATOR*

Potency of Arginine verified by GNC procedure #5115.

Clinically Researched

MegaNatural(R)-BP

resVida(R) promotes healthy aging

Product Details

DSLD Entry Date 2012-02-23
Product Type Other Combinations
Form Tablet or Pill
DSLD ID 5816
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

Compare Similar Products

View all Niacin products →