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St. Johnswort Plus

product on market Capsule Genestra Brands Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade
Label

Product Label

Label for St. Johnswort Plus
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Botanical
Product Type
0%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 300.0mg (240 products) 20 studies — no high-quality reviews
Market median: 300.0mg (240 products) 20 studies — no high-quality reviews

Other Ingredients

Hypromellose Cellulose
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Recommended Adult Dose: Take one capsule three times daily away from meals, or as recommended by your healthcare practitioner. May be used for up to six weeks.

Warnings & Precautions

Risk Information: If you are pregnant or breastfeeding, do not use.

If you experience sleep disturbances, consult your healthcare practitioner.

If you are taking conventional medication, such as contraceptives, HIV-1 protease inhibitors, non-nucleoside reverse transcriptase inhibitors, immunosuppressants, anticoagulants, digoxin, theophylline, serotonergic antidepressants, migraine therapies, SSRIs and/or anti-epilepsy drugs, consult your healthcare practitioner prior to use.

If symptoms persist, consult your healthcare practitioner. Avoid prolonged exposure to sunlight, ultraviolet light (UV) or UV therapy.

Quality Assurance: Safety-sealed for your protection and for product freshness. Do not use if outer seal is missing or broken.

Formulation Notes

Guaranteed to contain no added wheat, starch, yeast, gluten, corn, soy, sodium, sugar, artificial coloring or flavoring, antimicrobial preservatives, dairy or animal products.

Ideal for vegans.

The capsules are made from 100% pure vegetable sources, free of preservatives and additives.

Additional Information

Store in a cool, dry place.

Seroyal

460

Metadata

Product Details

UPC / SKU883196 11510
DSLD Entry Date2016-01-25
Product TypeBotanical
FormCapsule
DSLD ID55995
Data Updated2026-04-11
Research

Research Evidence

43
Research Sources
48
Avg Quality
16
Meta Analysis
14
Systematic Review
7
Rct
4
Regulatory Source
1
Clinical Trial
1
Openfda Safety
B St John's wort for major depression
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
B Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis
Meta Analysis Journal of affective disorders 2017 PubMed DOI
B A systematic review of St. John's wort for major depressive disorder
Meta Analysis Systematic reviews 2016 PubMed DOI
B St John's wort for depression
Systematic Review The Cochrane database of systematic reviews 2000 PubMed
B Efficacy of Pharmacological Interventions in Milder Depression: A Systematic Review and Meta-Analysis
Meta Analysis Neuropsychopharmacology reports 2025 PubMed DOI
B St John's wort for depression
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
C St John's wort for depression: meta-analysis of randomised controlled trials
Meta Analysis The British journal of psychiatry : the journal of mental science 2005 PubMed
C The effect of Hypericum perforatum on postmenopausal symptoms and depression: A randomized controlled trial
Rct Complementary therapies in medicine 2019 PubMed DOI
C Hypericum extract versus imipramine or placebo in patients with moderate depression: randomised multicentre study of treatment for eight weeks
Rct BMJ (Clinical research ed.) 1999 PubMed
C Hypericum perforatum as a cognitive enhancer in rodents: A meta-analysis
Meta Analysis Scientific reports 2016 PubMed DOI
View all evidence for St Johns Wort →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.