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St. John's Wort

product on market Capsule MRM Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade
Label

Product Label

Label for St. John's Wort
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Vegetarian Capsule(s)
Serving Size
60
Servings
Botanical
Product Type
0%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 300.0mg (240 products) 20 studies — no high-quality reviews

Other Ingredients

Rice Flour Capsule
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Usage: Take 1 capsule with a meal up to 2 times daily or as directed by your qualified healthcare provider.

Warnings & Precautions

WARNING: Do not use this product while taking any prescription drug(s) without the advice of your physician.

Formulation Notes

This material has been standardized to contain 0.3% Hypericins, known active components contained in the herb.

0.3% Hypericin

Contains NO milk, egg, peanut, tree nut, fish, shellfish, soy, wheat, gluten or yeast.

Additional Information

St. John’s Wort (Hypericum perforatum) is an herbal extract that has been used in Europe for years.

Research has indicated that hypericins interfere with particular enzymes in the brain that inhibit the “feel good” neurotransmitters such as serotonin, epinephrine and dopamine. St. John’s Wort is an effective nutritional supplement to support today’s stressful lifestyles.

~Enhances Mood & Well-Being ~Supports a Positive Mental Outlook ~Standardized to 0.3% Hypericins!

1014V002

Enhances Mood ~Supports a Positive Mental Outlook

PRODUCED IN A CERTIFIED FACILITY GMP GOOD MANUFACTURING PRACTICES

V CERTIFIED VEGAN VEGAN.ORG

Metadata

Product Details

UPC / SKU6 09492 54010
DSLD Entry Date2015-06-25
Product TypeBotanical
FormCapsule
BrandMRM
DSLD ID46629
Data Updated2026-04-11
Research

Research Evidence

43
Research Sources
48
Avg Quality
16
Meta Analysis
14
Systematic Review
7
Rct
4
Regulatory Source
1
Clinical Trial
1
Openfda Safety
B St John's wort for major depression
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
B Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis
Meta Analysis Journal of affective disorders 2017 PubMed DOI
B A systematic review of St. John's wort for major depressive disorder
Meta Analysis Systematic reviews 2016 PubMed DOI
B St John's wort for depression
Systematic Review The Cochrane database of systematic reviews 2000 PubMed
B Efficacy of Pharmacological Interventions in Milder Depression: A Systematic Review and Meta-Analysis
Meta Analysis Neuropsychopharmacology reports 2025 PubMed DOI
B St John's wort for depression
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
C St John's wort for depression: meta-analysis of randomised controlled trials
Meta Analysis The British journal of psychiatry : the journal of mental science 2005 PubMed
C The effect of Hypericum perforatum on postmenopausal symptoms and depression: A randomized controlled trial
Rct Complementary therapies in medicine 2019 PubMed DOI
C Hypericum extract versus imipramine or placebo in patients with moderate depression: randomised multicentre study of treatment for eight weeks
Rct BMJ (Clinical research ed.) 1999 PubMed
C Hypericum perforatum as a cognitive enhancer in rodents: A meta-analysis
Meta Analysis Scientific reports 2016 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.