🟢 90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Safety Alerts

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

1 Red Capsule(s) Serving Size
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

20 mg (100% DV)
✅ 1.4× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 20mg UL 35mg
Proprietary Thermogenic Blend
238.34 mg

Other Ingredients

Cellulose Gelatin Titanium Dioxide Artificial Colors

Label Claims — Verification

All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult Male (18-50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

DIRECTIONS: As a dietary supplement, take the contents of one pak daily first thing in the morning with food. Do not take prior to bed.

⚠️ Warnings & Precautions

WARNING: For adult use only.

Consult your physician prior to using this product if you are pregnant, nursing, taking medication or have a medical condition.

Discontinue use two weeks prior to surgery.

KEEP OUT OF REACH OF CHILDREN.

🧪 Formulation Notes

- Fuel Shredded Muscles and Supports Healthy Body Composition with 4g of Clinically Studied CLA

No Wheat, No Gluten, No Dairy, Yeast Free.

Total caffeine per capsule 200mg.

Additional Information

Athletes today are developing their speed, athleticism, muscle performance and complete physical potential faster than ever before. The ability to maintain a lean, ripped physique requires absolute fine-tuning of your sports nutrition regimen to enable the body to burn more calories, metabolize fats and achieve the best possible results from your training.

This elite breakthrough program is designed to maximize training effects, enhance calorie burning and support lean, toned muscles to achieve a healthy body composition. Most athletes today are not utilizing the proper combinations and ratios of critical sports nutrition. This system features potent supplements used by elite athletes and supplies what the muscles need to fuel intense training designed to deliver the ripped, lean body athletes want.

Thermo Igniter 12X- Push your performance to higher levels, increase energy and speed up metabolism. This clinically proven, proprietary thermogenic blend has been shown to help you burn 12 times more calories and increase your metabolism before , during and after exercise. In addition, just one capsule supports improved endurance and performance to help your body work longer and harder than ever before.

In a randomized, double-blind, placebo-controlled study of 112 healthy volunteers, subjects taking the GNC vitamin and mineral blend in this product for six weeks experienced statistically significant improvements in markers of B vitamins and antioxidant status, as well as improvements in SF-36 Vitality and Mental health scores compared to those taking a placebo.

In a double-blind, randomized, placebo-controlled cross-over study, 25 subjects exercised on a treadmill on two occasions. On one occasion the subjects took Thermo Igniter 12X and on the second occasion, they took a placebo. When the subjects took Thermo Igniter 12X, they burned three times more calories than before, 3% more calories during and 12 times more calories for up to one hour after exercise compared to when they took the placebo.

In an eight-week randomized double-blind placebo-controlled study of 30 healthy male volunteers comparing 1 set resistance training (RT) + active or carbohydrate placebo, to 2 sets RT alone with no supplement, the active group showed equal gains in maximal muscle strength (MMS) and muscle endurance (ME) compared to the control group.

ADVANCED MUSCLE PERFORMANCE

ADVANCED SPORTS VITAMIN SYSTEM TO FUEL A TIGHT CHISELED PHYSIQUE WITH OVER 50 POWERFUL INGREDIENTS

- Features GNC's Highest-Potency Sports Multivitamin to Fuel a Ripped Physique

- Burns 12 Times More Calories and Boosts Training Performance

- Helps to Regulate Excess Water

Daily Body Composition Energy Endurance

Clinically Researched

CODE 331911 ANG

{QRC} SCAN & LEARN

Store in a cool, dry place.

Thermo Igniter 12X

Conforms to USP <2091> for weight. Meets USP <2040> for disintegration.

{Capsule} ACTUAL SIZE

GNC QUALITY COMMITMENT For more than 75 years, GNC has been the leader in the development and manufacture of dietary supplements and is committed to producing the most superior products. We use only the highest quality ingredients manufactured under the strictest quality controls. Every raw material used is tested to ensure its purity and potency. Each product is dated and then shipped immediately to our stores to ensure that you are purchasing the freshest supplements available.

GNC GUARANTEE If you are not 100% completely satisfied, return the unused portion of the product with your receipt to a GNC store within 30 days. Our trained sales staff will either refund your purchase price or, if you prefer, assist you in finding a replacement product to help you LIVE WELL.

Product Details

DSLD Entry Date 2015-05-22
Product Type Other Combinations
Form Capsule
Bundle Mega Men Powered Ripped Vitapak Program
DSLD ID 45104
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
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