Home/ Supplements/ Creatine/ Amplified Creatine 189

Amplified Creatine 189

product on market Other (e.g. tea bag) GNC Pro Performance AMP Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

The PEG-Creatine system utilizes polyethylene glycol to enhance the solubility and absorption of creatine. Strong evidence supports the use of creatine for improving strength and muscle mass during high-intensity exercise. However, the specific efficacy of the PEG-delivery method compared to standard creatine monohydrate remains limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Amplified Creatine 189
Open Full PDF View on NIH DSLD →
Details

Label Data

2 White Caplet(s)
Serving Size
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 5.0mg (298 products) 705 studies (A:5, B:123)

Other Ingredients

Cellulose Dicalcium Phosphate Polyethylene Glycol Titanium Dioxide Enteric Coating natural Mint flavor Sucralose
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS: As a dietary supplement, take the contents of one pak 30-60 minutes per-workout. On non-training days, take the contents of one pak first thing in the morning with food.

To take muscular strength gains to new levels, stack with: - Amplified Muscle Igniter 4X – to improve physical and mental intensity - Amplified Mass XXX(TM) - provides a ratio of nutrients proven to accelerate increases in lean mass and exercise performance.

Warnings & Precautions

Discontinue use two weeks prior to surgery.

WARNING: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, under 18 years of age or have a medical condition.

KEEP OUT OF REACH OF CHILDREN.

Formulation Notes

Amplified Creatine 189(TM) - This advanced, cutting edge formula has been clinically proven to get in your muscles better than ordinary creatine.

Tribulus Terrestris & Anabolic Primer – Features high-quality Tribulus Terrestris and Fenugreek extract clinically studied to support anabolic muscle factors in the body.

- The Power of 5g of Creatine in 2 Tablets Delivers 189% Improved Muscle Creatine Absorption - Triggers Anabolic Factors with High-Quality Tribulus & Fenugreek

Amplified Creatine 189(TM)

No Wheat, No Gluten, No Dairy, Yeast Free.

Mega Men(R) Sport contains B-vitamins that are important for energy production and carbohydrate metabolism. It provides amino acids, including BCAA, and a joint cushioning blend for healthy joint cartilage. Also features a broad spectrum of cell-protecting antioxidants and nutrients that aid in boosting immunity.*

Additional Information

Creatine promotes cellular hydration and helps fuel muscles to improve and enhance athletic performance. This form increases strength with only 25% of the dose of ordinary creatine. In a clinical study, this form of creatine yielded 189% muscle creatine uptake relative to ordinary creatine monohydrate. This allows you to take less and get more into the muscle.

In a randomized, double-blind, placebo-controlled study of 112 healthy volunteers, subjects taking the GNC vitamin and mineral blend in this product for six weeks experienced statistically significant improvements in markers of B vitamins and antioxidant status, as well as improvements in SF-36 Vitality and Mental health scores compared to those taking a placebo. In a clinical study of 17 healthy young adults, muscle biopsy results revealed that GNC Pro Performance(R) AMP Amplified Creatine 189(TM) resulted in 189% greater muscle creatine uptake relative to benchmark amounts of ordinary creatine monohydrate powder. When used in conjunction with regular resistance training. In a randomized, double-blind clinicial study of 57 healthy young adult males, subjects who took, GNC Pro Performance(R) AMP Amplified Creatine 189(TM) containing only 1.25 grams creatine significantly improved leg press 1-RM performance by 54 lbs, while subjects on 5 grams of creatine monohydrate improved by 52 lbs, and the placebo group demonstrated no significant improvement when used in conjunction with regular resistance training.

ADVANCED MUSCLE PERFORMANCE

ADVANCED SPORTS VITAMIN SYSTEM TO ENHANCE STRENGTH TRAINING WITH OVER 50 POWERFUL INGREDIENTS

- Features GNC’s Highest-Potency Sports Multivitamin to Fuel Maximum Strength Training - Scientifically Formulated to Improve Upper and Lower Body Strength and Help Pack on Mass

Daily Strength Size Power

Clinically Researched

CODE 331811 ANG

Each pak contains:

{Caplet} Actual Size

Store in a cool, dry place.

{QRC} SCAN & LEARN MORE

GNC QUALITY COMMITMENT For more than 75 years, GNC has been the leader in the development and manufacture of dietary supplements, is committed to producing the most superior products. We use only the highest quality ingredients manufactured under the strictest quality controls. Every raw material used is tested to ensure its purity and potency. Each product is dated and then shipped immediately to our stores to ensure that you are purchasing the freshest supplements available.

GNC GUARANTEE If you are not 100% completely satisfied, return the unused portion of the product with your receipt to a GNC store within 30 days. Our trained sales staff will either refund your purchase price or, if you prefer, assist you in finding a replacement product to help you LIVE WELL.

Each performance boosting pak delivers GNC’s most optimal and precise combination of a premium daily multivitamin and sports nutrients. With over 50 powerful ingredients to support your total exercise strength training program, we’ve taken athletic performance nutrition to a whole new level. This scientifically mastered formula features a daily premium multivitamin and support nutrients combined with strength supporting mechanisms.

When activating the strength-building potential of this exclusive system, you amplify total strength results, increase muscular power and prepare your muscles to utilize the nutrients necessary to build mass with this complete training stack.* Most athletes today are not combining the proper combinations and ratios of critical sports nutrition.

Metadata

Product Details

DSLD Entry Date2015-02-25
Product TypeNon-Nutrient/Non-Botanical
FormOther (e.g. tea bag)
DSLD ID42327
Data Updated2026-04-11
Research

Research Evidence

739
Research Sources
47
Avg Quality
472
Clinical Trial
139
Meta Analysis
74
Systematic Review
47
Rct
2
Regulatory Source
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual Participant-Level Data
Meta Analysis JAMA psychiatry 2021 PubMed DOI
A HMG CoA reductase inhibitors (statins) for people with chronic kidney disease not requiring dialysis
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024 PubMed DOI
B Comparison of statins for secondary prevention in patients with ischemic stroke or transient ischemic attack: a systematic review and network meta-analysis
Systematic Review BMC medicine 2019 PubMed DOI
B Efficacy of Creatine Supplementation Combined with Resistance Training on Muscle Strength and Muscle Mass in Older Females: A Systematic Review and Meta-Analysis
Meta Analysis Nutrients 2021 PubMed DOI
B The Effects of Creatine Supplementation on Upper- and Lower-Body Strength and Power: A Systematic Review and Meta-Analysis
Meta Analysis Nutrients 2025 PubMed DOI
B Meta-analysis of the efficacy and safety of Finerenone in diabetic kidney disease
Meta Analysis Medicine 2026 PubMed DOI
B Creatine and creatine analogues in hypertension and cardiovascular disease
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
B HMG CoA reductase inhibitors (statins) for dialysis patients
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
View all evidence for Creatine →
Compare

Similar Products

View all Creatine products →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.