Homocysteine Blocker

product on market Tablet or Pill The Vitamin Shoppe 🟢 Safety: 100/100
Brand: The Vitamin Shoppe
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 75% of ingredients have research evidence
A Label Compliance Grade

Product Label

Label for Homocysteine Blocker
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Label Data

1 Tablet(s) Serving Size
Other Combinations Product Type
75% Evidence Coverage

Supplement Facts — Evidence Check

25 mg (1250% DV)
📊 19.2× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 25mg UL 100mg
400 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.4mg UL 1.0mg
250 mcg (4167% DV)
📊 104.2× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.25mg
500 mg
📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 500mg

Other Ingredients

Dicalcium Phosphate Microcrystalline Cellulose Stearic Acid Magnesium Stearate purified Water Hydroxypropyl Methylcellulose Polyethylene Glycol

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (98% of products) Structure/Function (89% of products) Nutrient (43% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

DIRECTIONS: As a dietary supplement, take one (1) to three (3) tablets daily, preferably with meals.

⚠️ Warnings & Precautions

TAMPER EVIDENT Do not use if outer seal is broken or missing.

WARNING: Consult your healthcare provider prior to use if you have a renal disorder, are pregnant, nursing, taking any medication or have any medical conditions.

KEEP OUT OF REACH OF CHILDREN.

🧪 Formulation Notes

gluten free dairy free soy free nut free

Does not contain: Yeast, Corn, Wheat, Gluten, Salt, Soy, Dairy, Fish, Preservatives, Artificial Colors or Flavors.

Additional Information

Visit www.vitaminshoppe.com or call 1-800-223-1216 for more information and to reorder.

{QRC} learn more at vsquality.net

Item No. VS-1776 1545854 BO 1

STORE IN A COOL, DRY PLACE.

specialty

cardiovascular

{tablet} actual size

Product Details

UPC / SKU 7 66536 01776 8
DSLD Entry Date 2014-08-26
Product Type Other Combinations
Form Tablet or Pill
Brand The Vitamin Shoppe
DSLD ID 35990
Data Updated 2026-04-11

Research Evidence

153 Research Sources
55 Avg Quality Score
71 Systematic Review
51 Meta Analysis
19 Rct
6 Clinical Trial
2 Other
2 Regulatory Source
1 Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013
PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009
PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
PubMed DOI Cochrane
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021
PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016
PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020
PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006
PubMed Cochrane
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022
PubMed DOI
View all evidence for Vitamin B6 →

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