🟢 90/100

This product looks safe

  • Folate: 200mg is 200.0× the Tolerable Upper Intake Level (1.0mg)
  • 50% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 200mg is 200.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Capsule(s) Serving Size
60 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

200 mcg DFE (50% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 200.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 200mg UL 1.0mg
500 mg
📊 Market median: 500.0mg (234 products) 📚 95 studies (Tier A: 0, B: 35)
This product: 500mg
Leucoselect Phytosome
50 mg
📊 Market median: 200.0mg (198 products) 📚 6 studies — no high-quality reviews
This product: 25mg

Other Ingredients

Hypromellose Microcrystalline Cellulose Leucine

Label Claims — Verification

All Other
All Other (100% of products) Structure/Function (86% of products) Nutrient (4% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free

Product Information

📋 Directions for Use

Suggested Use: As a dietary supplement, take 1 capsule, twice daily with food, or as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Warning: Do not take this product if pregnant or nursing. Caution: If taking p450 drugs, consult your healthcare practitioner before taking this product as Berberine may reduce the effectiveness of these drugs.

Keep out of reach of children.

To obtain product information or report a serious adverse event, call 1-800-325-1776.

Contains: Soy.

🧪 Formulation Notes

Color of this product may vary due to color variations of the natural ingredients.

Vegetarian

Gluten free Non-GMO

Additional Information

Truth We pledge total truth in labeling. Our family of products contains only the purest and most potent ingredients. Guaranteed.

Store in a cool, dry place.

Product Details

UPC / SKU 0 26664 00070 5
DSLD Entry Date 2025-09-25
Product Type Other Combinations
Form Capsule
DSLD ID 338002
Data Updated 2026-04-11

Research Evidence

98 Research Sources
55 Avg Quality Score
48 Systematic Review
39 Meta Analysis
4 Rct
4 Clinical Trial
1 Other
1 Narrative Review
1 Openfda Safety
B Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2018
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2023
B Effect of Berberine on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2019
B Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis The Journal of nutrition 2023
B The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
Meta Analysis Journal of translational medicine 2024
B Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature
Systematic Review International journal of molecular sciences 2024
B Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis The American journal of Chinese medicine 2019
B Effects of Berries, Phytochemicals, and Probiotics on Atherosclerosis through Gut Microbiota Modification: A Meta-Analysis of Animal Studies
Meta Analysis International journal of molecular sciences 2023
B Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial
Rct JAMA network open 2025
View all evidence for Berberine →

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