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Kidney Defender

product on market Capsule HEALTH DEFENDER A Nutraceutical company Safety: 70/100
70/100

Review before taking

  • Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 50% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Niacin is researched for its role in metabolic processes and lipid management, though evidence for kidney-specific support is limited. The proprietary blend lacks transparency, making it difficult to assess overall efficacy. Due to the low evidence coverage, the clinical support for this specific formulation is minimal.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)

Contains proprietary blend — exact ingredient amounts not disclosed

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product has a lower safety score because it contains an amount of Niacin that exceeds the recommended daily upper limit. Additionally, it uses a proprietary blend, meaning the exact amounts of some ingredients are not disclosed.

Label

Product Label

Label for Kidney Defender
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
60
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

100 mg (625% DV)
Exceeds UL by 2.9× (UL: 35 mg) 196 studies (A:5, B:63)
Proprietary Blend
1292 mg

Other Ingredients

Cellulose Rice Flour
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions for use: Take 2 capsules before each meal; 2x a day.

Warnings & Precautions

Warning: Keep out of the reach of children.

Consult with your health care practitioner if you are trying to get pregnant, nursing, taking other medications, or have other conditions.

This product is commonly used by those with most stages of CKD. Do not use if the safety seal is broken or missing. Always consult with your health care provider before starting any new supplement regiment.

Formulation Notes

Kidney & GFR support

Gluten-free - GMP Certified

Gluten-free - GMP Certified

Additional Information

Store in a cool, dry place.

Metadata

Product Details

UPC / SKU1 98715 68703 3
DSLD Entry Date2025-08-22
Product TypeOther Combinations
FormCapsule
DSLD ID336838
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.