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Defend & Resist Complex

product on market Tablet or Pill Shaklee Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains zinc and echinacea, which have moderate evidence for supporting immune function and reducing the duration of common colds. Larch tree extract is included, though research on its specific efficacy is more limited. The ingredient profile is considered safe for general use.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Defend & Resist Complex
Open Full PDF View on NIH DSLD →
Details

Label Data

6 Tablet(s)
Serving Size
15
Servings
Botanical with Nutrients
Product Type
33%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
15 Calorie(s)
Total Carbohydrates
4 Gram(s) (1% DV)
15 mg (136% DV)
1.4× RDA — within safe limits 263 studies (A:6, B:134)
Market median: 400.0mg (380 products) 36 studies (A:1, B:10)
Larch Tree Extract
300 mg
Defend & Resist Proprietary Blend
480 mg

Other Ingredients

Maltose Microcrystalline Cellulose
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take 6 tablets daily for about 7 days. Swallow, chew, or drink as a tea.

Warnings & Precautions

Caution: If pregnant or nursing, consult your physician prior to use.

Seal under cap for your protection.

Manufactured in a facility that may also process tree nuts, milk, soy, wheat, and fish.

Formulation Notes

Bolsters your immune system with immunoactive polysaccharides and polyphenos from extracts of echinacea, black elderberry, and larch tree to stimulate the body's natural resistance during seasonal changes plus zinc to support healthy immune function.

Kosher

GF Gluten free No artificial flavors, sweeteners, colors, or preservatives

Supercharge your immune system

Additional Information

Shaklee Since 1956 Safe - Proven 100% Guaranteed Kosher

Dr Shaklee

Metadata

Product Details

DSLD Entry Date2025-07-24
Product TypeBotanical with Nutrients
FormTablet or Pill
BrandShaklee
DSLD ID334645
Data Updated2026-04-11
Research

Research Evidence

397
Research Sources
55
Avg Quality
200
Meta Analysis
68
Rct
58
Systematic Review
53
Clinical Trial
9
Cochrane Review
2
Narrative Review
2
Regulatory Source
1
Observational
1
Other
1
Openfda Safety
A Zinc supplementation for improving pregnancy and infant outcome
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
A Zinc supplementation for preventing mortality, morbidity, and growth failure in children aged 6 months to 12 years
Narrative Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Oral zinc for treating diarrhoea in children
Meta Analysis The Cochrane database of systematic reviews 2016 PubMed DOI
A Zinc supplements for preventing otitis media
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Zinc for the prevention or treatment of acute viral respiratory tract infections in adults: a rapid systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ open 2021 PubMed DOI
A Zinc supplements for preventing otitis media
Meta Analysis The Cochrane database of systematic reviews 2010 PubMed DOI
A Zinc supplements for preventing otitis media
Meta Analysis The Cochrane database of systematic reviews 2012 PubMed DOI
A Compression bandages or stockings versus no compression for treating venous leg ulcers
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
A Zinc supplementation for mental and motor development in children
Meta Analysis The Cochrane database of systematic reviews 2012 PubMed DOI
A Zinc for the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
View all evidence for Zinc →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.