Defend & Resist Complex by Shaklee — Ingredients, Evidence & Safety

Product Label

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Label Data

6 Tablet(s) Serving Size

15 Servings

Botanical with Nutrients Product Type

33% Evidence Coverage

Supplement Facts — Evidence Check

Calories

15 Calorie(s)

Total Carbohydrates

4 Gram(s) (1% DV)

Zinc

15 mg (136% DV)

✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 15mg UL 40mg

Echinacea Herb, Root Extract

168 mg

📊 Market median: 400.0mg (380 products) 📚 34 studies (Tier A: 1, B: 10)

This product: 168mg

Larch Tree Extract

300 mg

Defend & Resist Proprietary Blend

480 mg

Other Ingredients

Maltose Microcrystalline Cellulose

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (84% of products) Nutrient (48% of products)

Target Groups

Adult (18 - 50 Years) Kosher Gluten Free

Product Information

📋 Directions for Use

Directions: Take 6 tablets daily for about 7 days. Swallow, chew, or drink as a tea.

⚠️ Warnings & Precautions

Caution: If pregnant or nursing, consult your physician prior to use.

Seal under cap for your protection.

Manufactured in a facility that may also process tree nuts, milk, soy, wheat, and fish.

🧪 Formulation Notes

Bolsters your immune system with immunoactive polysaccharides and polyphenos from extracts of echinacea, black elderberry, and larch tree to stimulate the body's natural resistance during seasonal changes plus zinc to support healthy immune function.

Kosher

GF Gluten free No artificial flavors, sweeteners, colors, or preservatives

Supercharge your immune system

Additional Information

Shaklee Since 1956 Safe - Proven 100% Guaranteed Kosher

Dr Shaklee

Product Details

DSLD Entry Date 2025-07-24

Product Type Botanical with Nutrients

Form Tablet or Pill

Brand Shaklee

DSLD ID 334645

Data Updated 2026-04-11

Research Evidence

397 Research Sources

55 Avg Quality Score

200 Meta Analysis

68 Rct

58 Systematic Review

53 Clinical Trial

9 Cochrane Review

2 Narrative Review

2 Regulatory Source

1 Observational

1 Other

1 Openfda Safety

A Zinc supplementation for improving pregnancy and infant outcome

Meta Analysis The Cochrane database of systematic reviews 2021

PubMed DOI Cochrane

A Zinc supplementation for preventing mortality, morbidity, and growth failure in children aged 6 months to 12 years

Narrative Review The Cochrane database of systematic reviews 2023

PubMed DOI Cochrane

A Oral zinc for treating diarrhoea in children

Meta Analysis The Cochrane database of systematic reviews 2016

PubMed DOI

A Zinc supplements for preventing otitis media

Meta Analysis The Cochrane database of systematic reviews 2014

PubMed DOI Cochrane

A Zinc for the prevention or treatment of acute viral respiratory tract infections in adults: a rapid systematic review and meta-analysis of randomised controlled trials

Meta Analysis BMJ open 2021

PubMed DOI

A Zinc supplements for preventing otitis media

Meta Analysis The Cochrane database of systematic reviews 2010

PubMed DOI Cochrane

A Zinc supplements for preventing otitis media

Meta Analysis The Cochrane database of systematic reviews 2012

PubMed DOI Cochrane

A Compression bandages or stockings versus no compression for treating venous leg ulcers

Meta Analysis The Cochrane database of systematic reviews 2021

PubMed DOI

A Zinc supplementation for mental and motor development in children