🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

📸

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Label Data

1 Capsule(s) Serving Size
90 Servings
Botanical Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 300.0mg (240 products) 📚 11 studies — no high-quality reviews
This product: 450mg

Other Ingredients

Brown Rice, Powder Hypromellose Magnesium Stearate Microcrystalline Cellulose

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (2% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions Adults (18 years and older) - Take 1 capsule, 2 times per day. Use for at least 1 week to see beneficial effects. Consult a healthcare professional for use beyond 18 weeks.

⚠️ Warnings & Precautions

Warnings Do not use this product if you are taking anti-cancer medications, antidepressant [e.g. selective serotonin reuptake inhibitors (SSRI)], cardiovascular medications, contraceptive medications, blood thinners, anti-HIV agents, medications to suppress the immune system (immunosuppressive medications). Consult a healthcare professional prior to use if you are pregnant, you are breastfeeding, you are taking antianxiety medications, you are taking seizure medications, you are taking antihistamines, you are taking bronchodilators, you are taking muscle relaxants, you are taking opiates.

Avoid prolonged exposure to sunlight, ultraviolet light (UV), UV therapy. Consult a healthcare professional if symptoms persist or worsen. Some people may experience mild gastrointestinal disturbances, nausea, restlessness and headaches.

Keep out of reach of children.

Other information Do not use if safety seal is broken.

Stop use if hypersensitivity/allergy occurs.

🧪 Formulation Notes

Professional Naturopathic Formulations Made in Canada

Uses Helps promote healthy mood balance and relieve sleep disturbances associated with mood imbalance. Traditionally used in Herbal Medicine to help relieve restlessness and nervousness.

Vegan.

GMO, gluten, soy and dairy free.

Additional Information

NPN 80114463

Peel for more information

Questions? Reach us at info@cytomatrix.co Cytomatrix.ca

Product Details

UPC / SKU 8 71740 00164 6
DSLD Entry Date 2025-09-25
Product Type Botanical
Form Capsule
Brand Cyto-Matrix
DSLD ID 334487
Data Updated 2026-04-11

Research Evidence

43 Research Sources
48 Avg Quality Score
16 Meta Analysis
14 Systematic Review
7 Rct
4 Regulatory Source
1 Clinical Trial
1 Openfda Safety
B St John's wort for major depression
Systematic Review The Cochrane database of systematic reviews 2008
B Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis
Meta Analysis Journal of affective disorders 2017
B A systematic review of St. John's wort for major depressive disorder
Meta Analysis Systematic reviews 2016
B St John's wort for depression
Systematic Review The Cochrane database of systematic reviews 2000
B Efficacy of Pharmacological Interventions in Milder Depression: A Systematic Review and Meta-Analysis
Meta Analysis Neuropsychopharmacology reports 2025
B St John's wort for depression
Meta Analysis The Cochrane database of systematic reviews 2005
C St John's wort for depression: meta-analysis of randomised controlled trials
Meta Analysis The British journal of psychiatry : the journal of mental science 2005
C The effect of Hypericum perforatum on postmenopausal symptoms and depression: A randomized controlled trial
Rct Complementary therapies in medicine 2019
C Hypericum extract versus imipramine or placebo in patients with moderate depression: randomised multicentre study of treatment for eight weeks
Rct BMJ (Clinical research ed.) 1999
C Hypericum perforatum as a cognitive enhancer in rodents: A meta-analysis
Meta Analysis Scientific reports 2016
View all evidence for St Johns Wort →

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