🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Tablet(s) Serving Size
60 Servings
Other Combinations Product Type
33% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)
This product: 102.5mg
Beef Liver, Powder
100 mg
100 mg
📊 Market median: 500.0mg (193 products) 📚 7 studies — no high-quality reviews
This product: 100mg
✅ Within RDA (0.1× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 50mg UL 3500mg
50 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 50mg
📊 Market median: 300.0mg (159 products)
Median 300.0mg This product: 50mg
Alfalfa, Powder
17.5 mg
Black Radish, Powder
2.5 mg
Goldenseal, Powder
2.5 mg

Other Ingredients

Microcrystalline Cellulose Croscarmellose Sodium Stearic Acid Magnesium Stearate Silicon Dioxide Hydroxypropyl Methylcellulose Polyethylene Glycol Titanium Dioxide Food Drug & Cosmetic Red #40 Food Drug & Cosmetic Yellow #6 Food Drug & Cosmetic Blue #1 Food Drug & Cosmetic Blue #2

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Directions: For adults, take one (1) tablet upon rising and one at bedtime. Follow with a large glass of water, best if taken on an empty stomach.

⚠️ Warnings & Precautions

As a reminder, discuss the supplements and medications you take with your health care providers. Warning: If you are pregnant, nursing, taking any medications or have any medical conditions, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Tamper resistant: Do not use if imprinted seal under cap is broken or missing.

🧪 Formulation Notes

Made in USA

Maintains healthy liver function Helps detox liver

Additional Information

Esmondnatural integrated health

Store in a dry place and avoid excessive heat.

1994 Quality You Can Trust GMP Good Manufacturing Practices

Product Details

UPC / SKU 0 641399 781905
DSLD Entry Date 2025-06-25
Product Type Other Combinations
Form Tablet or Pill
DSLD ID 334332
Data Updated 2026-04-11

Research Evidence

69 Research Sources
55 Avg Quality Score
34 Meta Analysis
26 Systematic Review
5 Rct
3 Clinical Trial
1 Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024
View all evidence for Milk Thistle →

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