🟢 87/100

This product is generally safe

  • Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
  • 67% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
67% Evidence Coverage

Supplement Facts — Evidence Check

680 mcg DFE (170% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 680.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 680mg UL 1.0mg
📊 Market median: 200.0mg (3 products) 📚 10 studies (Tier A: 1, B: 3)
This product: 100mg
Sunflower Lecithin
25 mg

Other Ingredients

Rice Concentrate Vegetable Capsule Silica

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (77% of products) Nutrient (60% of products) Approved Health (5% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Suggested use: Adults take one (1) capsule daily, preferably with a meal or as directed by a healthcare practitioner.

⚠️ Warnings & Precautions

Warnings: Keep out of reach of children.

Do not exceed recommended dose. Do not use if clear neck seal is broken or missing.

If you are nursing, pregnant, taking medication or have a medical condition, consult your physician before taking this product.

🧪 Formulation Notes

(Diindolymethane 100 mg)

Supports healthy hormone balance and metabolism

Clean label

V

Non GMO Gluten free

Additional Information

Store at room temperature, in a dry place.

V Manufactured in U.S.A. with quality ingredients from around the world

Product Details

DSLD Entry Date 2025-09-25
Product Type Other Combinations
Form Capsule
DSLD ID 333610
Data Updated 2026-04-11

Research Evidence

363 Research Sources
57 Avg Quality Score
187 Meta Analysis
56 Systematic Review
54 Rct
29 Guideline
26 Clinical Trial
6 Cochrane Review
2 Regulatory Source
1 Other
1 Openfda Safety
A Homocysteine-lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
Meta Analysis Digestive diseases and sciences 2021
A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021
A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrients 2024
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2022
A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
Meta Analysis Critical reviews in food science and nutrition 2023
A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care
Meta Analysis The Cochrane database of systematic reviews 2025
View all evidence for Folate →

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