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5-HTP 200 mg Time Release

product on market Tablet or Pill Natrol Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

5-Hydroxytryptophan is used to support serotonin levels, with moderate evidence suggesting its role in managing mood and sleep. Calcium serves as a basic mineral for bone and nerve function. Overall, clinical evidence for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP 200 mg Time Release
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
60
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calcium
55 mg (4% DV)
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)

Other Ingredients

Microcrystalline Cellulose Hypromellose Stearic Acid Silicon Dioxide Magnesium Stearate Methylcellulose Glycerin
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Adults, take 1 tablet daily with a meal.

Warnings & Precautions

Warning: Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, or are taking medication or have a medical condition; including drugs for depression, migraines, Parkinson's disease or psychiatric disorders. Do not use with other supplements containing L-Tryptophan or 5-HTP.

Do not use with other supplements containing L-tryptophan or 5-HTP.

Warning: Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, or are taking medication or have a medical condition; including drugs for depression, migraines, Parkinson's disease or psychiatric disorders. Keep out of reach of children.

Do not exceed suggested intake.

Do not use if safety seal is damaged or missing.

Formulation Notes

Natrol 5-HTP 200 mg Time Release: Promotes production of Serotonin throughout the day

Mood & stress Time released Helps support a balanced mood

100% drug-free No: Milk, Egg, Fish, Crustacean Shellfish, Tree Nuts, Peanuts, Wheat, Soybeans, Sesame

Additional Information

Store in a cool, dry place.

Metadata

Product Details

UPC / SKU0 47469 07443 2
DSLD Entry Date2025-07-24
Product TypeOther Combinations
FormTablet or Pill
BrandNatrol
DSLD ID332252
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.