🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Tablet(s) Serving Size
45 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

Calcium
32 mg (2% DV)
📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 100mg

Other Ingredients

Hypromellose Microcrystalline Cellulose Stearic Acid Silicon Dioxide Magnesium Stearate Methylcellulose Glycerin

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (52% of products)

Target Groups

Adult (18 - 50 Years) Dairy Free

Product Information

📋 Directions for Use

Suggested use: Adults, take 1 tablet, up to two times daily with a meal.

⚠️ Warnings & Precautions

Warning: Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, or are taking medication or have a medical condition; including drugs for depression, migraines, Parkinson's disease or psychiatric disorders.

Warning: Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, or are taking medication or have a medical condition; including drugs for depression, migraines, Parkinson's disease or psychiatric disorders. Keep out of reach of children.

Do not use with other supplements containing L-Tryptophan or 5-HTP. If adverse reactions occur, discontinue use.

Do not exceed recommended intake.

Do not use if safety seal is damaged or missing.

🧪 Formulation Notes

Natrol 5-HTP 100 mg Time Release: Controlled release tablet releases 5-HTP slowly to help support a balanced mood and promote production of serotonin throughout the day.

Mood + Stress Helps support a balanced mood Promotes production of serotonin throughout the day

100% Drug free

No: Milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat, soybeans, sesame

Additional Information

Store in a cool, dry place.

Product Details

UPC / SKU 0 47469 05228 7
DSLD Entry Date 2025-06-25
Product Type Other Combinations
Form Tablet or Pill
Brand Natrol
DSLD ID 332249
Data Updated 2026-04-11

Research Evidence

21 Research Sources
53 Avg Quality Score
11 Systematic Review
6 Rct
4 Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025
View all evidence for 5 Htp →

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