St. John's Wort Supreme 450 mg

product on market Capsule Supreme Nutrition Products 🟢 Safety: 100/100
Brand: Supreme Nutrition Products
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size
45 Servings
Botanical Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

900 mg
📊 Market median: 300.0mg (240 products) 📚 11 studies — no high-quality reviews
This product: 900mg

Other Ingredients

Cellulose

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (2% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

Suggested use: 1-2 capsules 3 times per day.

⚠️ Warnings & Precautions

Do not take if pregnant or breastfeeding. This herb can interact with antidepressants, oral contraceptives, and other prescription medications. Consult your physician before taking if on any prescription medicine.

Avoid excessive exposure to UV radiation while taking.

Keep out of reach of children.

Product Details

UPC / SKU 1 98168 95515 4
DSLD Entry Date 2025-04-24
Product Type Botanical
Form Capsule
Brand Supreme Nutrition Products
DSLD ID 327337
Data Updated 2026-04-11

Research Evidence

43 Research Sources
48 Avg Quality Score
16 Meta Analysis
14 Systematic Review
7 Rct
4 Regulatory Source
1 Clinical Trial
1 Openfda Safety
B St John's wort for major depression
Systematic Review The Cochrane database of systematic reviews 2008
PubMed DOI
B Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis
Meta Analysis Journal of affective disorders 2017
PubMed DOI
B A systematic review of St. John's wort for major depressive disorder
Meta Analysis Systematic reviews 2016
PubMed DOI
B St John's wort for depression
Systematic Review The Cochrane database of systematic reviews 2000
PubMed
B Efficacy of Pharmacological Interventions in Milder Depression: A Systematic Review and Meta-Analysis
Meta Analysis Neuropsychopharmacology reports 2025
PubMed DOI
B St John's wort for depression
Meta Analysis The Cochrane database of systematic reviews 2005
PubMed
C St John's wort for depression: meta-analysis of randomised controlled trials
Meta Analysis The British journal of psychiatry : the journal of mental science 2005
PubMed
C The effect of Hypericum perforatum on postmenopausal symptoms and depression: A randomized controlled trial
Rct Complementary therapies in medicine 2019
PubMed DOI
C Hypericum extract versus imipramine or placebo in patients with moderate depression: randomised multicentre study of treatment for eight weeks
Rct BMJ (Clinical research ed.) 1999
PubMed
C Hypericum perforatum as a cognitive enhancer in rodents: A meta-analysis
Meta Analysis Scientific reports 2016
PubMed DOI
View all evidence for St Johns Wort →

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