SAMe 200 mg
This product looks safe
- No ingredients exceed tolerable upper intake levels
- 100% of ingredients have research evidence
What the Evidence Says
AI-generated · Qwen 3.6 · grounded in 1 source · methodologySAMe is researched for its potential to support mood regulation and joint health. There is moderate evidence suggesting its efficacy in managing depressive symptoms when compared to certain antidepressants. Clinical data on its overall impact remains limited due to low evidence coverage.
AI-generated summary based on research evidence. Not medical advice.
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Label Data
Supplement Facts — Evidence Check
Other Ingredients
Label Claims — Verification
Product Information
Directions for Use
Suggested usage: Take 1 capsule 2 to 4 times daily, or as directed by your healthcare practitioner.
Warnings & Precautions
Cautions/interactions: Theoretically, SAMe could increase the effects and adverse effects of products that increase serotonin levels, including 5-hydroxytryptophan (5-HTP), Hawaiian baby woodrose, L-tryptophan, and St. John's wort.
In addition, SAMe may interact with MAO inhibitors, L-Dopa, antidepressants and other serotonergic drugs. Consult healthcare practitioner if pregnant/nursing, taking medication, or have a medical condition, especially bipolar or anxiety disorders.
Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.
Formulation Notes
How it works: SAMe (S-adenosylmethionine), a compound native to the body, is a critical component of many biochemical reactions, including those that affect brain biochemistry and joint health. Numerous studies have indicated that SAMe can help to alleviate transient normal aches and pains resulting from overexertion or stress. In addition, because SAMe is also necessary for the synthesis of neurotransmitters, it plays an important role in the maintenance of a positive mood.
Natural color variation may occur in this product. Supports nervous system and joint health No enteric coating needed
Stabilized SAMe, capsule form
Non-GMO
Vegetarian/vegan
Made in Canada with globally sourced ingredients.
Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients.
Additional Information
Refrigeration recommended after opening.
Product Details
Research Evidence
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.