🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

📸

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Label Data

1 Tablet(s) Serving Size
60 Servings
Amino acid/Protein Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

1000 mg
📊 Market median: 500.0mg (70 products)
Median 500.0mg This product: 1000mg

Other Ingredients

Croscarmellose Sodium Hydroxypropyl Cellulose Stearic Acid Magnesium Stearate Vegetarian Coating Silicon Dioxide

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (100% of products) Structure/Function (90% of products) Nutrient (61% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested usage: Take 1 tablet 1 to 2 times daily on an empty stomach, with final dose at bedtime, or as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Cautions/interactions: Tryptophan supplements may interact with CNS depressants, antidepressants (SSRIs, MAOIs), and other serotonergic agents such as St. John's Wort and 5-HTP. May cause drowsiness. Do not use with alcoholic beverages or while operating heavy machinery.

Consult your healthcare practitioner if you are taking medications or herbs, are pregnant/nursing, or if you have liver impairment.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

🧪 Formulation Notes

How it works: Tryptophan is an essential amino acid; therefore, it is not synthesized by the body and must be obtained from the diet. In the brain, tryptophan is converted into serotonin, a neurotransmitter involved in feelings of well-being, calmness, personal security, and relaxation. It also plays a role in the regulation of appetite and synchronization of sleep patterns.

Every lot of Protocol For Life Balance L-Tryptophan is tested to be free of peak E and microbial contamination.

Encourages positive mood Supports relaxation & restful sleep

Non-GMO

Vegetarian/vegan

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.

Natural color variation may occur in this product.

Product Details

UPC / SKU 7 07359 10169 2
DSLD Entry Date 2025-03-25
Product Type Amino acid/Protein
Form Tablet or Pill
DSLD ID 326452
Data Updated 2026-04-11

Research Evidence

29 Research Sources
48 Avg Quality Score
19 Rct
5 Meta Analysis
3 Systematic Review
2 Clinical Trial
B Prebiotic and probiotic supplementation and the tryptophan-kynurenine pathway: A systematic review and meta analysis
Meta Analysis Neuroscience and biobehavioral reviews 2021
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002
B The impact of tryptophan supplementation on sleep quality: a systematic review, meta-analysis, and meta-regression
Meta Analysis Nutrition reviews 2022
B No effects of acute tryptophan depletion on anxiety or mood in weight-recovered female patients with anorexia nervosa
Rct European archives of psychiatry and clinical neuroscience 2023
C The association between tryptophan levels and postpartum mood disorders: a systematic review and meta-analysis
Meta Analysis BMC psychiatry 2022
C A systematic review of the effect of L-tryptophan supplementation on mood and emotional functioning
Systematic Review Journal of dietary supplements 2021
C Comparison between Acupuncture and Nutraceutical Treatment with Migratens® in Patients with Fibromyalgia Syndrome: A Prospective Randomized Clinical Trial.
Rct Nutrients
C Intake of Lactiplantibacillus plantarum HEAL9 Improves Cognition in Moderately Stressed Subjects: A Randomized Controlled Study.
Rct Nutrients
C Are tryptophan and 5-hydroxytryptophan effective treatments for depression? A meta-analysis
Meta Analysis The Australian and New Zealand journal of psychiatry 2002
View all evidence for Tryptophan →

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