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L-Tryptophan 1000 mg

product on market Tablet or Pill Protocol For Life Balance Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade
Label

Product Label

Label for L-Tryptophan 1000 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
60
Servings
Amino acid/Protein
Product Type
0%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

1000 mg
Market median: 500.0mg (70 products)

Other Ingredients

Croscarmellose Sodium Hydroxypropyl Cellulose Stearic Acid Magnesium Stearate Vegetarian Coating Silicon Dioxide
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested usage: Take 1 tablet 1 to 2 times daily on an empty stomach, with final dose at bedtime, or as directed by your healthcare practitioner.

Warnings & Precautions

Cautions/interactions: Tryptophan supplements may interact with CNS depressants, antidepressants (SSRIs, MAOIs), and other serotonergic agents such as St. John's Wort and 5-HTP. May cause drowsiness. Do not use with alcoholic beverages or while operating heavy machinery.

Consult your healthcare practitioner if you are taking medications or herbs, are pregnant/nursing, or if you have liver impairment.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Formulation Notes

How it works: Tryptophan is an essential amino acid; therefore, it is not synthesized by the body and must be obtained from the diet. In the brain, tryptophan is converted into serotonin, a neurotransmitter involved in feelings of well-being, calmness, personal security, and relaxation. It also plays a role in the regulation of appetite and synchronization of sleep patterns.

Every lot of Protocol For Life Balance L-Tryptophan is tested to be free of peak E and microbial contamination.

Encourages positive mood Supports relaxation & restful sleep

Non-GMO

Vegetarian/vegan

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.

Natural color variation may occur in this product.

Metadata

Product Details

UPC / SKU7 07359 10169 2
DSLD Entry Date2025-03-25
Product TypeAmino acid/Protein
FormTablet or Pill
DSLD ID326452
Data Updated2026-04-11
Research

Research Evidence

29
Research Sources
48
Avg Quality
19
Rct
5
Meta Analysis
3
Systematic Review
2
Clinical Trial
B Prebiotic and probiotic supplementation and the tryptophan-kynurenine pathway: A systematic review and meta analysis
Meta Analysis Neuroscience and biobehavioral reviews 2021 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of tryptophan supplementation on sleep quality: a systematic review, meta-analysis, and meta-regression
Meta Analysis Nutrition reviews 2022 PubMed DOI
B No effects of acute tryptophan depletion on anxiety or mood in weight-recovered female patients with anorexia nervosa
Rct European archives of psychiatry and clinical neuroscience 2023 PubMed DOI
C The association between tryptophan levels and postpartum mood disorders: a systematic review and meta-analysis
Meta Analysis BMC psychiatry 2022 PubMed DOI
C A systematic review of the effect of L-tryptophan supplementation on mood and emotional functioning
Systematic Review Journal of dietary supplements 2021 PubMed DOI
C Comparison between Acupuncture and Nutraceutical Treatment with Migratens® in Patients with Fibromyalgia Syndrome: A Prospective Randomized Clinical Trial.
Rct Nutrients PubMed DOI
C Intake of Lactiplantibacillus plantarum HEAL9 Improves Cognition in Moderately Stressed Subjects: A Randomized Controlled Study.
Rct Nutrients PubMed DOI
C Are tryptophan and 5-hydroxytryptophan effective treatments for depression? A meta-analysis
Meta Analysis The Australian and New Zealand journal of psychiatry 2002 PubMed
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.