🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
Amino acid/Protein Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

1 Gram(s)
📊 Market median: 500.0mg (70 products)
Median 500.0mg This product: 1mg

Other Ingredients

Cellulose Stearic Acid Croscarmellose Sodium Magnesium Stearate Silica Vegetarian Coating

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (90% of products) Nutrient (61% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested Usage: Take 1 tablet 1 to 2 times daily on an empty stomach, with final dose at bedtime, or as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Cautions/Interactions: Tryptophan supplements may interact with CNS depressants, antidepressants (SSRIs, MAOIs), and other serotonergic agents such as St. John's Wort and 5-HTP. Consult your healthcare practitioner if you are taking medications or herbs, are pregnant/nursing, or if you have liver impairment.

May cause drowsiness. Do not use with alcoholic beverages or while operating heavy machinery.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Do not eat freshness packet. Keep in bottle.

🧪 Formulation Notes

Every lot of Protocol For Life Balance L-Tryptophan is tested to be free of Peak E and microbial contamination.

Vegetarian/Vegan

Non-GMO

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.

Additional Information

How It Works: L-Tryptophan is an essential amino acid; therefore, it is not synthesized by the body and must be obtained from the diet. In the brain, Tryptophan is converted into serotonin, a neurotransmitter involved in feelings of well-being, calmness, personal security, and relaxation.* It also plays a role in the regulation of appetite and synchronization of sleep patterns.*

CODE P0169 V5

~ Encourages positive mood* ~ Supports relaxation & restful sleep*

Non-GMO

Natural color variation may occur in this product.

Product Details

UPC / SKU 7 07359 10169 2
DSLD Entry Date 2017-04-25
Product Type Amino acid/Protein
Form Tablet or Pill
DSLD ID 72895
Data Updated 2026-04-11

Research Evidence

29 Research Sources
48 Avg Quality Score
19 Rct
5 Meta Analysis
3 Systematic Review
2 Clinical Trial
B Prebiotic and probiotic supplementation and the tryptophan-kynurenine pathway: A systematic review and meta analysis
Meta Analysis Neuroscience and biobehavioral reviews 2021
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002
B The impact of tryptophan supplementation on sleep quality: a systematic review, meta-analysis, and meta-regression
Meta Analysis Nutrition reviews 2022
B No effects of acute tryptophan depletion on anxiety or mood in weight-recovered female patients with anorexia nervosa
Rct European archives of psychiatry and clinical neuroscience 2023
C The association between tryptophan levels and postpartum mood disorders: a systematic review and meta-analysis
Meta Analysis BMC psychiatry 2022
C A systematic review of the effect of L-tryptophan supplementation on mood and emotional functioning
Systematic Review Journal of dietary supplements 2021
C Comparison between Acupuncture and Nutraceutical Treatment with Migratens® in Patients with Fibromyalgia Syndrome: A Prospective Randomized Clinical Trial.
Rct Nutrients
C Intake of Lactiplantibacillus plantarum HEAL9 Improves Cognition in Moderately Stressed Subjects: A Randomized Controlled Study.
Rct Nutrients
C Are tryptophan and 5-hydroxytryptophan effective treatments for depression? A meta-analysis
Meta Analysis The Australian and New Zealand journal of psychiatry 2002
View all evidence for Tryptophan →

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