🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 43% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 Vegetarian Capsule(s) Serving Size
45 Servings
Other Combinations Product Type
43% Evidence Coverage

Supplement Facts — Evidence Check

Total Carbohydrates
1 Gram(s) (1% DV)
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 500mg
📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)
This product: 400mg
📊 Market median: 375.0mg (171 products) 📚 30 studies (Tier A: 1, B: 14)
This product: 100mg
White Willow Bark Extract
50 mg
📊 Market median: 100.0mg (173 products)
Median 100.0mg This product: 10mg
Bioperine
5 mg

Other Ingredients

Cellulose Rice Husk Concentrate Rice Bran Extract

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (89% of products) Nutrient (7% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, adults take two (2) capsules daily with any meal or as directed by a healthcare provider.

⚠️ Warnings & Precautions

Do not exceed recommended dosage. Individual results may vary. Stop use and contact a physician if adverse reactions occur. Do not use if product appears to be tampered with or seal is broken.

Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.

Keep out of reach of children.

🧪 Formulation Notes

21st Century Arthri-Flex Advantage + Turmeric is a combination of Glucosamine HCL and Turmeric Root Extract along with supportive herbal ingredients. This vegan formula includes 5 mg of Black Pepper Extract to help support bioavailability of Turmeric, as it is not easily assimilated by our bodies.

No added sugar, salt, yeast, wheat, soy, dairy, preservatives, artificial colors or flavors. Gluten free. Non-GMO.

Glucosamine HCL, turmeric & black pepper extract 500 mg glucosamine HCL per serving 400 mg turmeric extract per serving

Joint health support Joint & mobility support

Vegan

Additional Information

Store at room temperature.

New

Guaranteed Quality Laboratory Tested

Product Details

UPC / SKU 7 40985 27924 3
DSLD Entry Date 2025-01-23
Product Type Other Combinations
Form Capsule
Brand 21st Century
DSLD ID 326309
Data Updated 2026-04-11

Research Evidence

311 Research Sources
54 Avg Quality Score
121 Systematic Review
98 Meta Analysis
70 Rct
16 Clinical Trial
2 Other
1 Narrative Review
1 Openfda Safety
A The efficacy and safety of Curcuma longa extract and curcumin supplements on osteoarthritis: a systematic review and meta-analysis
Meta Analysis Bioscience reports 2021
B Curcumin for depression: a meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2020
B Effect of Aromatic Herbs and Spices Present in the Mediterranean Diet on the Glycemic Profile in Type 2 Diabetes Subjects: A Systematic Review and Meta-Analysis
Meta Analysis Nutrients 2024
B Complementary and Alternative Medicine Therapies for Psoriasis: A Systematic Review
Meta Analysis JAMA dermatology 2018
B Functional foods modulating inflammation and metabolism in chronic diseases: a systematic review
Systematic Review Critical reviews in food science and nutrition 2022
B Effect of curcumin supplementation on symptoms of anxiety: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2024
B The efficacy of high- and low-dose curcumin in knee osteoarthritis: A systematic review and meta-analysis
Meta Analysis Complementary therapies in medicine 2021
B Efficacy of Curcumin-Mediated Antimicrobial Photodynamic Therapy on Candida spp.-A Systematic Review
Systematic Review International journal of molecular sciences 2024
B Effects of curcumin on serum inflammatory biomarkers in patients with knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials
Meta Analysis BMC complementary medicine and therapies 2025
B Natural Products in Alzheimer's Disease: A Systematic Review of Clinical Trials and Underlying Molecular Mechanisms
Systematic Review International journal of molecular sciences 2025
View all evidence for Curcumin →

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