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St. John's Wort 450 mg

product on market Capsule Solaray Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade
Label

Product Label

Label for St. John's Wort 450 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

2 VegCap(s)
Serving Size
50
Servings
Botanical
Product Type
0%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 300.0mg (240 products) 20 studies — no high-quality reviews

Other Ingredients

Cellulose
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Use only as directed. Take two VegCaps twice daily with a meal or glass of water.

Warnings & Precautions

Warning: Do not use if safety seal is broken or missing. Keep your licensed health care practitioner informed when using this product. Due to the potential photosensitizing properties of St. John's Wort, avoid prolonged exposure to the sun.

Keep out of reach of children.

If you are pregnant, nursing or taking a prescription MAO inhibitor, consult your physician before using this product.

California residents only Warning: Reproductive harm - www.P65Warnings.ca.gov

Formulation Notes

Hypericum perforatum 450 mg per capsule

Whole aerial

Discussion: Solaray St. John's Wort aerial is 100% vegan, excipient-free and contain no fillers or additional ingredients.

Discussion: Solaray St. John's Wort aerial is 100% vegan, excipient-free and contain no fillers or additional ingredients.

Additional Information

Lab Verified

Store in a cool, dry place.

Metadata

Product Details

UPC / SKU0 76280 19553 8
DSLD Entry Date2025-01-23
Product TypeBotanical
FormCapsule
BrandSolaray
DSLD ID326123
Data Updated2026-04-11
Research

Research Evidence

43
Research Sources
48
Avg Quality
16
Meta Analysis
14
Systematic Review
7
Rct
4
Regulatory Source
1
Clinical Trial
1
Openfda Safety
B St John's wort for major depression
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
B Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis
Meta Analysis Journal of affective disorders 2017 PubMed DOI
B A systematic review of St. John's wort for major depressive disorder
Meta Analysis Systematic reviews 2016 PubMed DOI
B St John's wort for depression
Systematic Review The Cochrane database of systematic reviews 2000 PubMed
B Efficacy of Pharmacological Interventions in Milder Depression: A Systematic Review and Meta-Analysis
Meta Analysis Neuropsychopharmacology reports 2025 PubMed DOI
B St John's wort for depression
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
C St John's wort for depression: meta-analysis of randomised controlled trials
Meta Analysis The British journal of psychiatry : the journal of mental science 2005 PubMed
C The effect of Hypericum perforatum on postmenopausal symptoms and depression: A randomized controlled trial
Rct Complementary therapies in medicine 2019 PubMed DOI
C Hypericum extract versus imipramine or placebo in patients with moderate depression: randomised multicentre study of treatment for eight weeks
Rct BMJ (Clinical research ed.) 1999 PubMed
C Hypericum perforatum as a cognitive enhancer in rodents: A meta-analysis
Meta Analysis Scientific reports 2016 PubMed DOI
View all evidence for St Johns Wort →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.