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Niacin 250 mg

product on market Capsule Pure Naturals Safety: 60/100
60/100

Review before taking

  • Niacin: 250mg is 7.1× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Niacin is used to support cholesterol levels and cardiovascular health, with strong evidence supporting these effects. However, the low safety score indicates potential concerns, such as the risk of flushing or liver toxicity at certain doses. Users should be aware of these possible adverse reactions.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 250mg is 7.1× the Tolerable Upper Intake Level (35mg)

✨ AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because the amount of Niacin is more than seven times the recommended upper limit for daily intake.

Label

Product Label

Label for Niacin 250 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
180
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

250 mg (1250% DV)
Exceeds UL by 7.1× (UL: 35 mg) 196 studies (A:5, B:63)

Other Ingredients

Sucrose Gelatin Corn Starch Food Glaze Magnesium Silicate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: As a dietary supplement, adults take one (1) capsule daily, preferably with a meal or as directed by a healthcare professional.

Warnings & Precautions

Warning: Not intended for use by pregnant or nursing women. If you are taking medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse.

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Formulation Notes

Time release capsules Promotes energy production Supports cardiovascular health Supports healthy circulation

Contains no: artificial color, artificial preservatives, artificial flavor or sweetener, sugar, starch, milk, lactose, soy, gluten, wheat, yeast or sodium.

Additional Information

Store in a cool, dry place.

Sourced from a GMP Certified Facility Good Manufacturing Practice Quality Assured Made in USA

Metadata

Product Details

UPC / SKU8 19070 01441 7
DSLD Entry Date2025-02-23
Product TypeVitamin
FormCapsule
BrandPure Naturals
DSLD ID323868
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.