Appe-Curb

product on market Capsule NuMedica 🟢 Safety: 100/100
Brand: NuMedica
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 57% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

4 Capsule(s) Serving Size
60 Servings
Other Combinations Product Type
57% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin C
500 mg (556% DV)
37.5 mg (2206% DV)
📊 28.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 37.5mg UL 100mg
60 mcg (171% DV)
✅ 1.7× RDA — within safe limits 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.06mg
DL-Phenylalanine
1000 mg
750 mg
📊 Market median: 500.0mg (223 products) 📚 22 studies (Tier A: 0, B: 1)
This product: 750mg
375 mg
📊 Market median: 420.0mg (227 products)
Median 420.0mg This product: 375mg
75 mg
📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 75mg

Other Ingredients

Hydroxypropyl Methylcellulose Magnesium Stearate Silicon Dioxide

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (54% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: Take four capsules before breakfast and four capsules before lunch or as directed by your healthcare practitioner. Do not take after 3 PM.

⚠️ Warnings & Precautions

Caution: Keep out of reach of children.

🧪 Formulation Notes

Appe-Curb contains neurotransmitter precursors and conversion nutrients that help satisfy the "reward cascade" of the brain. Satisfying the "reward cascade" of the brain may help with cravings for things that may be appealing such as drugs, alcohol and carbohydrates while improving mood and increasing energy. By helping to restore major brain neurotransmitters, Appe-Curb may support balance in the brain and a feeling of well-being.

This formula meets or exceeds cGMP Quality Standards.

Does not contain: Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy.

Professional quality formulas Nutritional support for drugs, alcohol & carbohydrate cravings Neurotransmitter support

GF Gluten free

Vegetarian

Additional Information

Storage: Keep tightly closed in a cool, dry place. Keep away from direct sunlight.

Product Details

UPC / SKU 8 12527 01054 3
DSLD Entry Date 2025-05-21
Product Type Other Combinations
Form Capsule
Brand NuMedica
DSLD ID 323494
Data Updated 2026-04-11

Research Evidence

371 Research Sources
54 Avg Quality Score
148 Meta Analysis
82 Systematic Review
71 Rct
62 Clinical Trial
2 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Other
1 Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
PubMed DOI Cochrane
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017
PubMed DOI Cochrane
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013
PubMed DOI Cochrane
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013
PubMed DOI Cochrane
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020
PubMed DOI Cochrane
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021
PubMed DOI Cochrane
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024
PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024
PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021
PubMed DOI
View all evidence for Vitamin C →

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