Home/ Supplements/ Folate/ B-6 B-12 Folic Acid Berry

B-6 B-12 Folic Acid Berry

product on market Tablet or Pill KAL Safety: 87/100
87/100

This product is generally safe

  • Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Vitamin B6, B12, and folate are essential nutrients that support energy metabolism and neurological function. There is strong evidence that these vitamins play critical roles in homocysteine regulation and red blood cell formation. This combination is generally well-tolerated and safe for most individuals.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for B-6 B-12 Folic Acid Berry
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
60
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

3 mg (176% DV)
2.3× RDA — within safe limits 114 studies (A:3, B:35)
680 mcg DFE (170% DV)
Exceeds UL by 680.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
1000 mcg (41667% DV)
416.7× RDA — above typical dose 139 studies (A:1, B:44)

Other Ingredients

Mannitol Starch Complex Cellulose Berry Flavor, Natural Other Natural Flavors Polysaccharides Sorbitol Magnesium Stearate Stevia Leaf Extract Silica Citric Acid Sodium Bicarbonate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

1 Daily

Directions: Dissolve one ActivMelt micro tablet on or under the tongue daily. Use only as directed.

Warnings & Precautions

Warning: Do not use if safety seal is broken or missing. Keep your licensed health care practitioner informed when using this product.

Keep out of reach of children.

Folate intake should not exceed 250% of the DV (1000 mcg) for pregnant women.

Formulation Notes

Healthy energy support ActivMelt Instant Dissolve

B-6 B-12 Folic Acid 3mg / 1000mcg/ 680mcg DFE Berry Natural Flavor

Discussion: KAL B-6 B-12 Folic Acid ActivMelt micro tablets melt quickly in the mouth and are designed for optimal absorption in the body. P-5-P B-6, Methyl B-12 & Folic Acid are intended to work synergistically to provide nutritive support for healthy cardiovascular function through red blood cell synthesis, and supporting protein metabolism and normal homocysteine levels.

Vegetarian.

Additional Information

Store in a cool, dry place.

Metadata

Product Details

UPC / SKU0 21245 65185 7
DSLD Entry Date2025-02-23
Product TypeVitamin
FormTablet or Pill
BrandKAL
DSLD ID322891
Data Updated2026-04-11
Research

Research Evidence

363
Research Sources
57
Avg Quality
187
Meta Analysis
56
Systematic Review
54
Rct
29
Guideline
26
Clinical Trial
6
Cochrane Review
2
Regulatory Source
1
Other
1
Openfda Safety
A Homocysteine-lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
Meta Analysis Digestive diseases and sciences 2021 PubMed DOI
A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021 PubMed DOI
A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrients 2024 PubMed DOI
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2022 PubMed DOI
A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.