Home/ Supplements/ Folate/ L-5-MTHF 25,500 mcg DFE

L-5-MTHF 25,500 mcg DFE

product on market Capsule Seeking Health Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade
Label

Product Label

Label for L-5-MTHF 25,500 mcg DFE
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Vitamin
Product Type
0%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Quatrefolic
25500 mcg (6375% DV)

Other Ingredients

L-Glycine Hypromellose Water
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Take 1 capsule daily, or use as directed by your healthcare professional.

Warnings & Precautions

Do not take within 5 hours of bedtime as it may interfere with sleep. Do not use if tamper seal is damaged.

Caution: Children and pregnant or lactating women should consult their healthcare professional prior to use. Storage: Keep closed in a cool, dry place out of reach of children.

Caution: Children and pregnant or lactating women should consult their healthcare professional prior to use.

Formulation Notes

L-5-MTHF supports healthy methylation using a bioactive, superior form of methylfolate.

Does not contain: Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy, gluten, GMO, artificial colors, or artificial flavors.

L-5-MTHF meets or exceed cGMP Quality Standards.

L-Methylfolate 25,500 mcg DFE

Additional Information

Find other effective health products at www.seekinghealth.com This package is completely recyclable.

Manufactured in the USA from globally sourced ingredients Third-party independently tested

Storage: Keep closed in a cool, dry place out of reach of children.

Metadata

Product Details

UPC / SKU8 10007 52180 0
DSLD Entry Date2024-11-22
Product TypeVitamin
FormCapsule
DSLD ID322656
Data Updated2026-04-11
Research

Research Evidence

363
Research Sources
57
Avg Quality
187
Meta Analysis
56
Systematic Review
54
Rct
29
Guideline
26
Clinical Trial
6
Cochrane Review
2
Regulatory Source
1
Other
1
Openfda Safety
A Homocysteine-lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
Meta Analysis Digestive diseases and sciences 2021 PubMed DOI
A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021 PubMed DOI
A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrients 2024 PubMed DOI
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2022 PubMed DOI
A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.