Home/ Supplements/ Electrolytes/ Cramprin +BioPerine

Cramprin +BioPerine

product on market Tablet or Pill Approved Science Safety: 92/100
92/100

This product looks safe

  • Magnesium: 420mg is 1.2× the Tolerable Upper Intake Level (350mg)
  • 60% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula combines magnesium and B vitamins, which have moderate evidence for supporting muscle and nerve function. Ginger and chamomile are included for their traditional use in managing inflammation and relaxation, though clinical evidence for these specific dosages is limited. BioPerine is added to potentially enhance the absorption of other ingredients.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Magnesium: 420mg is 1.2× the Tolerable Upper Intake Level (350mg)

Label

Product Label

Label for Cramprin +BioPerine
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
30
Servings
Botanical with Nutrients
Product Type
60%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

420 mg (100% DV)
Exceeds UL by 1.2× (UL: 350 mg) 316 studies (A:8, B:159)
Market median: 400.0mg (142 products) 10 studies (A:0, B:2)
Market median: 250.0mg (337 products) 127 studies (A:1, B:41)
BioPerine
5 mg

Other Ingredients

Dicalcium Phosphate Microcrystalline Cellulose Stearic Acid Magnesium Stearate Silicon Dioxide
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take two tablets daily, (one in the morning and one in the afternoon), before meals with an 8 oz. glass of water.

Warnings & Precautions

Caution: Do not exceed recommended dose. Do not use if safety seal is damaged or missing.

Pregnant women or nursing mothers, children under 18, and individuals with a known medical condition, should consult with a physician before taking this or any other dietary supplement.

Pregnant women or nursing mothers, children under 18, and individuals with a known medical condition, should consult with a physician before taking this or any other dietary supplement. Keep out of reach of children.

Formulation Notes

Manufactured in the USA according to current Good Manufacturing Practice (cGMP) and conforms to the tested ingredients grade, strength and purity of industry Quality Standards.

Vegan friendly

Made with GMO free ingredients

Advanced leg cramp support Premium grade High potency Safe Fast Natural formula Optimal strength GMP Certified

Cramprin +BioPerine with Magnesium Glycinate

100% vegan friendly

Additional Information

Store at room temperature.

Vegan friendly Made in USA No animal testing GMP Good Manufacturing Practice Quality Product

Metadata

Product Details

UPC / SKUX002TOSK67
DSLD Entry Date2024-10-24
Product TypeBotanical with Nutrients
FormTablet or Pill
BrandApproved Science
DSLD ID319745
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
View all evidence for Electrolytes →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.