🟡 60/100

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  • Nicotinamide Riboside Chloride: 1000mg is 28.6× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Nicotinamide Riboside Chloride: 1000mg is 28.6× the Tolerable Upper Intake Level (35mg)

This product received a low safety score because the amount of Nicotinamide Riboside Chloride in a single dose is significantly higher than the recommended maximum daily limit.

Label Data

2 Vegetarian Capsule(s) Serving Size
30 Servings
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

⚠️ Exceeds Tolerable Upper Intake Level by 28.6× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 1000mg UL 35mg

Other Ingredients

Hypromellose Microcrystalline Cellulose Rice Flour

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (100% of products) Structure/Function (90% of products) Nutrient (28% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Dairy Free

Product Information

📋 Directions for Use

Suggested Use Take two (2) capsules daily with or without food. May be taken with or without food.

⚠️ Warnings & Precautions

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using.

Do not use if safety seal is broken or missing.

🧪 Formulation Notes

Ultrapure Nicotinamide Riboside in delayed release, enteric-coated capsules.

This product is manufactured in the United States at a FDA registered facility under strict GMP standards.

Enteric capsules

No artificial colors, flavors or preservatives. Non-GMO.

Suitable for vegans.

Enteric capsules resist degradation in the highly acidic environment of the stomach to protect the payload from digestion.

Nicotinamide riboside

Additional Information

GMP Good Manufacturing Practice Certified

Store in a cool, dry place.

Product Details

UPC / SKU 8 50055 68510 9
DSLD Entry Date 2024-09-25
Product Type Vitamin
Form Capsule
DSLD ID 319005
Data Updated 2026-04-11

Research Evidence

10 Research Sources
49 Avg Quality Score
8 Rct
1 Systematic Review
1 Clinical Trial
B Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults
Rct Nature communications 2018
C The effects of NAD+ precursor (nicotinic acid and nicotinamide) supplementation on weight loss and related hormones: a systematic review and meta-regression analysis of randomized controlled trials
Systematic Review Frontiers in nutrition 2023
C Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial.
Rct Nature aging
C Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults
Rct Scientific reports 2019
C Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures
Rct Cell reports 2019
C Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin
Rct Aging cell 2023
C Nicotinamide riboside with pterostilbene (NRPT) increases NAD+ in patients with acute kidney injury (AKI): a randomized, double-blind, placebo-controlled, stepwise safety study of escalating doses of NRPT in patients with AKI
Rct BMC nephrology 2020
C Clinical Trial of Niagen to Examine Recovery in People With Persistent Cognitive and Physical Symptoms After COVID-19
Clinical Trial ClinicalTrials.gov 2021
C A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individuals.
Rct JCI insight
C Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double-Blind Randomized Crossover Placebo-Controlled Trial.
Rct Aging cell
View all evidence for Nicotinamide Riboside →

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