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NR 1000

product on market Capsule Renue By Science Safety: 60/100
60/100

Review before taking

  • Nicotinamide Riboside Chloride: 1000mg is 28.6× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Nicotinamide Riboside Chloride is researched for its role in increasing NAD+ levels to support cellular energy. Evidence for these effects in humans remains limited. Due to a lower safety score, potential side effects or contraindications should be considered.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Nicotinamide Riboside Chloride: 1000mg is 28.6× the Tolerable Upper Intake Level (35mg)

✨ AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because it contains 1000mg of Nicotinamide Riboside Chloride, which is nearly 29 times higher than the recommended upper intake limit.

Label

Product Label

Label for NR 1000
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Vegetarian Capsule(s)
Serving Size
30
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Exceeds UL by 28.6× (UL: 35 mg) 196 studies (A:5, B:63)

Other Ingredients

Hypromellose Microcrystalline Cellulose Rice Flour
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use Take two (2) capsules daily with or without food. May be taken with or without food.

Warnings & Precautions

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using.

Do not use if safety seal is broken or missing.

Formulation Notes

Ultrapure Nicotinamide Riboside in delayed release, enteric-coated capsules.

This product is manufactured in the United States at a FDA registered facility under strict GMP standards.

Enteric capsules

No artificial colors, flavors or preservatives. Non-GMO.

Suitable for vegans.

Enteric capsules resist degradation in the highly acidic environment of the stomach to protect the payload from digestion.

Nicotinamide riboside

Additional Information

GMP Good Manufacturing Practice Certified

Store in a cool, dry place.

Metadata

Product Details

UPC / SKU8 50055 68510 9
DSLD Entry Date2024-09-25
Product TypeVitamin
FormCapsule
BrandRenue By Science
DSLD ID319005
Data Updated2026-04-11
Research

Research Evidence

10
Research Sources
49
Avg Quality
8
Rct
1
Systematic Review
1
Clinical Trial
B Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults
Rct Nature communications 2018 PubMed DOI
C The effects of NAD+ precursor (nicotinic acid and nicotinamide) supplementation on weight loss and related hormones: a systematic review and meta-regression analysis of randomized controlled trials
Systematic Review Frontiers in nutrition 2023 PubMed DOI
C Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial.
Rct Nature aging PubMed DOI
C Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults
Rct Scientific reports 2019 PubMed DOI
C Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures
Rct Cell reports 2019 PubMed DOI
C Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin
Rct Aging cell 2023 PubMed DOI
C Nicotinamide riboside with pterostilbene (NRPT) increases NAD+ in patients with acute kidney injury (AKI): a randomized, double-blind, placebo-controlled, stepwise safety study of escalating doses of NRPT in patients with AKI
Rct BMC nephrology 2020 PubMed DOI
C Clinical Trial of Niagen to Examine Recovery in People With Persistent Cognitive and Physical Symptoms After COVID-19
Clinical Trial ClinicalTrials.gov 2021
C A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individuals.
Rct JCI insight PubMed DOI
C Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double-Blind Randomized Crossover Placebo-Controlled Trial.
Rct Aging cell PubMed DOI
View all evidence for Nicotinamide Riboside →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.