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Digestive Enzyme Formula

product on market Other (e.g. tea bag) Puritan's Pride Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 8% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains amylase and bromelain, which have moderate evidence for supporting the breakdown of carbohydrates and proteins. Betaine hydrochloride is used to increase stomach acid, while calcium and phosphorus serve as mineral supports. Overall, clinical evidence for this specific combination of ingredients is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Digestive Enzyme Formula
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Caplet(s)
Serving Size
30
Servings
Other Combinations
Product Type
8%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calcium
150 mg (12% DV)
118 mg (9% DV)
Within RDA (0.2× RDA) 13 studies (A:0, B:3)
Market median: 496.0mg (192 products) 20 studies — no high-quality reviews
Amylase
108 mg
80 mg
Market median: 200.0mg (136 products) 3 studies — no high-quality reviews
Market median: 60.0mg (107 products) 1 studies — no high-quality reviews
Protease
30 mg
Papain
20 mg
Pepsin
20 mg
Lipase
12.5 mg
Cellulase
10 mg
Pancreatin
4 mg

Other Ingredients

Dicalcium Phosphate Cellulose Tapioca Dextrin Maltodextrin Lactose Stearic Acid Silica Tapioca Starch, Modified Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: For adults, take two (2) caplets daily, preferably with a meal.

Warnings & Precautions

Warning: If you are pregnant, nursing, taking any medications or have any medical condition, including a known sensitivity to latex, consult your doctor before use.

Warning: If you are pregnant, nursing, taking any medications or have any medical condition, including a known sensitivity to latex, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Contains milk, wheat and soy ingredients.

Formulation Notes

This product contains natural enzymes that sometimes have a distinctive odor.

Digestive aid for proteins, fats & carbohydrates

Additional Information

Store at room temperature.

To reorder item # 13011 www.puritan.com 1-800-645-1030

QA Quality Assured

Metadata

Product Details

UPC / SKU0 25077 13011 5
DSLD Entry Date2024-09-25
Product TypeOther Combinations
FormOther (e.g. tea bag)
BrandPuritan's Pride
DSLD ID318301
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
View all evidence for Electrolytes →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.