Home/ Supplements/ Niacin/ B-3 Niacinamide 500 mg

B-3 Niacinamide 500 mg

product on market Capsule NutraBio Safety: 60/100
60/100

Review before taking

  • Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Niacin supports energy metabolism and skin health, with strong evidence for its role in cellular function. However, the safety score indicates potential concerns, as high doses may cause flushing or liver stress in some individuals. Evidence coverage for this specific formulation remains limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)

✨ AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because it contains 500mg of Niacin, which is over 14 times the recommended maximum daily limit.

Label

Product Label

Label for B-3 Niacinamide 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Vegetable Capsule(s)
Serving Size
120
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

500 mg NE (3130% DV)
Exceeds UL by 14.3× (UL: 35 mg) 196 studies (A:5, B:63)

Other Ingredients

Hypromellose Water
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: Take 1 capsule daily as needed, preferably with meals.

Warnings & Precautions

Warning: Keep out of reach of children. Not for use by individuals under the age of 18.

Do not use if pregnant or nursing. Consult a physician before use if you have a medical condition or are taking any medication.

Discontinue use two weeks prior to surgery.

Processed in a facility and/or manufacturing line that also produces milk, tree nuts, nuts and soy.

Formulation Notes

Check. Verify. Trust. View Independent Lab Results Checkmysupps.com No proprietary blends Fully transparent

Flush free niacin

No added color, flavor, sweetener, or preservatives. Manufactured without lactose or gluten.

Gluten free Non-GMO Lactose free

OU (Kosher)

Additional Information

Check. Verify. Trust. View Independent Lab Results Checkmysupps.com No proprietary blends Fully transparent

Manufactured in our GMP & FDA inspected facility

Made in USA With ingredients sourced worldwide

Wellness

Store in a cool dry place.

OU (Kosher)

Product filled to this level

Metadata

Product Details

UPC / SKU6 49908 52086 1
DSLD Entry Date2024-09-25
Product TypeVitamin
FormCapsule
BrandNutraBio
DSLD ID318062
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.