Apple Cider Vinegar Gummies 500 mg by up&up — Ingredients, Evidence & Safety

🟢 92/100

This product looks safe

Folate: 200mg is 200.0× the Tolerable Upper Intake Level (1.0mg)
40% of ingredients have research evidence

C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 200mg is 200.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Gummy(ies) Serving Size

60 Servings

Botanical with Nutrients Product Type

40% Evidence Coverage

Supplement Facts — Evidence Check

Calories

10 Calorie(s)

Total Carbohydrates

3 Gram(s) (1% DV)

Folate

200 mcg DFE (50% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 200.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 200mg UL 1.0mg

Vitamin B12

1.2 mcg (50% DV)

✅ Within RDA (0.5× RDA of 0.0024 mg) 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.0012mg

Apple Cider Vinegar

500 mg

Other Ingredients

Tapioca Sugar Water, Purified Pectin Citric Acid Natural Flavor Sodium Citrate Malic Acid Carrot Beet Blackcurrant Pomegranate Rice Flour

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (77% of products) Nutrient (60% of products) Approved Health (5% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Organic Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested use: adults, 1-2 gummies up to 3 times daily (up to 6 gummies a day).

⚠️ Warnings & Precautions

Keep out of reach of children.

Warning: pregnant or nursing women, individuals taking medication(s) or persons who have a health condition should consult their physician before using this product.

Safety sealed. Do not use if printed seal under cap is cut, torn or missing.

Processed on equipment which utilizes coconut MCT oil.

🧪 Formulation Notes

General wellness Taste the goodness. Not the vinegar. Enjoy the many health benefits of apple cider vinegar without the unpleasant taste. A delicious and nutritious way to support your well-being.

Gluten free, organic, non-GMO, gelatin free and vegan.

No artificial dyes or flavors No gluten No lactose Does not contain: yeast, wheat, milk, eggs, gluten, soy, gelatin, peanuts, shellfish, dairy, artificial sweetener, artificial colors, artificial flavors, agave, artificial preservatives and salicylates. Gluten free

Made in a FDA registered and cGMP certified facility in the USA.

Enjoy the benefits of apple cider vinegar without the strong taste Certified organic with the mother

Certified organic with the mother

Certified Organic by: MCIA

Additional Information

Store at 15 degrees-30 degrees C (59 degrees-86 degrees F)

Compare to Goli Gummies This product is not manufactured or distributed by Goli Nutrition Inc., owner of the registered trademark Goli.

Questions? Call 1-800-910-6874

Product Details

DSLD Entry Date 2024-08-22

Product Type Botanical with Nutrients

Form Gummy or Jelly

Brand up&up

DSLD ID 317811

Data Updated 2026-04-11

Research Evidence

363 Research Sources

57 Avg Quality Score

187 Meta Analysis

56 Systematic Review

54 Rct

29 Guideline

26 Clinical Trial

6 Cochrane Review

2 Regulatory Source

1 Other

1 Openfda Safety

A Homocysteine-lowering interventions for preventing cardiovascular events

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI

A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI

A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies

Meta Analysis Digestive diseases and sciences 2021

PubMed DOI

A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis

Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021

PubMed DOI

A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Meta Analysis Nutrients 2024

PubMed DOI

A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis

Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025

PubMed DOI

A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies

Meta Analysis Critical reviews in food science and nutrition 2019

PubMed DOI

A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials

Meta Analysis Critical reviews in food science and nutrition 2022

PubMed DOI

A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants

Meta Analysis Critical reviews in food science and nutrition 2023

PubMed DOI

A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care

Meta Analysis The Cochrane database of systematic reviews 2025

PubMed DOI

View all evidence for Folate →