Super Formula #1 OC-Classic by Physician's Signature — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
20% of ingredients have research evidence

B Label Compliance Grade

Product Label

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Label Data

1 Softgel(s) Serving Size

180 Servings

Other Combinations Product Type

20% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin B12

3 mcg (125% DV)

✅ 1.3× RDA — within safe limits 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.003mg

Royal Jelly

45 mg

📊 Market median: 303.0mg (42 products)

This product: 45mg

Rose Hip Extract

25 mg

Alpha-Lipoic Acid

5 mg

📊 Market median: 200.0mg (198 products) 📚 6 studies — no high-quality reviews

This product: 5mg

Bee Pollen

0.4 mg

Other Ingredients

Soybean Oil Sodium Alginate Yellow Beeswax Lecithin Disodium Edetate Maltodextrin Dicalcium Phosphate Silica Microcrystalline Cellulose Gelatin Glycerin Water Caramel Titanium Dioxide

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (89% of products) Nutrient (56% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested Use: Take one softgel capsule, twice daily or as directed by a healthcare professional.

⚠️ Warnings & Precautions

Caution: Consult your physician prior to using this product if you are pregnant, nursing, or have any pre-existing medical conditions.

Keep out of the reach of children

Do not use if seal is broken

Contains: soy.

🧪 Formulation Notes

Super Formula #1 offers excellent support for the cardiovascular system by providing Vitamin B12 along with targeted ingredients such as Alpha Lipoic Acid, Rosehips extract, chelating agents like Royal Jelly, sodium alginate, and EDTA.

Note: The color, taste, and texture of this product may vary due to its natural ingredients and/or seasonal changes.

Super Formula #1 OC-Classic with royal jelly

Additional Information

Store in a cool, dry place

Product Details

UPC / SKU 8 54755 00724 7

DSLD Entry Date 2024-08-22

Product Type Other Combinations

Form Softgel Capsule

Brand Physician's Signature

DSLD ID 316964

Data Updated 2026-04-11

Research Evidence

237 Research Sources

53 Avg Quality Score

83 Meta Analysis

74 Systematic Review

45 Rct

29 Clinical Trial

2 Guideline

2 Regulatory Source

1 Openfda Safety

A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis

Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025

PubMed DOI

A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies

Meta Analysis Critical reviews in food science and nutrition 2019

PubMed DOI

A Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency

Systematic Review The Cochrane database of systematic reviews 2018

PubMed DOI Cochrane

A Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression

Meta Analysis Nutrients 2021

PubMed DOI

A Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta-analysis

Systematic Review Irish journal of medical science 2024

PubMed DOI

B Helicobacter pylori infection and micronutrient deficiency in pregnant women: a systematic review and meta-analysis

Meta Analysis BMJ open gastroenterology 2020

PubMed DOI

B Vitamin B12 supplementation during pregnancy for maternal and child health outcomes

Systematic Review The Cochrane database of systematic reviews 2024

PubMed DOI Cochrane

B A comprehensive review and meta-regression analysis of randomized controlled trials examining the impact of vitamin B12 supplementation on homocysteine levels

Meta Analysis Nutrition reviews 2024

PubMed DOI

B Relationship between vitamin B12 levels and motor development: A systematic review

Systematic Review Clinical nutrition ESPEN 2024

PubMed DOI

B Vitamin B12, folate, and homocysteine in metabolic syndrome: a systematic review and meta-analysis

Meta Analysis Frontiers in endocrinology 2023

PubMed DOI

View all evidence for Vitamin B12 →