🟡 60/100

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  • Nicotinamide: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Nicotinamide: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)

The safety score is low because the amount of nicotinamide in this supplement significantly exceeds the recommended maximum daily intake limit.

Label Data

1 Veggie Capsule(s) Serving Size
100 Servings
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

500 mg (2500% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 14.3× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 500mg UL 35mg

Other Ingredients

Cellulose Microcrystalline Cellulose Leucine

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free

Product Information

📋 Directions for Use

Suggested use: As a dietary supplement, take 1 veggie capsule daily, or as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Warning: Do not use if pregnant or nursing.

If you are diabetic, have liver disease, or stomach ulcers, consult your healthcare practitioner before taking this product. It is recommended to discontinue use 2 weeks before any surgery.

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

🧪 Formulation Notes

Formulated to support energy production Metabolism Circulation Nerve & digestive function Synthesis of sex hormones Color of this product may vary due to color variations of the natural ingredients FDA Registered Facility USA Manuf. in USA w/ Global Ingred.

Supports energy production

GMP Good Manuf. Practices

Gluten Free

Vegetarian

Non Flush Niacin

Made w/ Non GMO Ingred. No Artificial Colors

Additional Information

Store sealed in a cool, dry place.

Product Details

UPC / SKU X001KO1VR7
DSLD Entry Date 2024-07-25
Product Type Vitamin
Form Capsule
Brand Dr. Seth's
DSLD ID 315778
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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